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• Tsai, Y
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Molecules 2012, 17(9), 10724-10737; doi:10.3390/molecules170910724

Article

Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans

Chien-Ya Hung* , Yu-Cheng Tsai and Kuo-Yu Li

Department of Food Nutrition, Chung Hwa University of Medical Technology, No.89, Wenhua 1st St., Rende Dist., Tainan City 71703, Taiwan

* Author to whom correspondence should be addressed.

Received: 21 July 2012; in revised form: 21 August 2012 / Accepted: 5 September 2012 / Published: 7 September 2012

(This article belongs to the Section Natural Products)

Download PDF Full-Text [267 KB, uploaded 7 September 2012 08:49 CEST]

Abstract: O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl₃ sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC₅₀ values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H₂O₂ scavenging ability, with IC₅₀ values of 10.5, 23.4, and 13.4 μM, respectively.

Keywords: Osmanthus fragrans; Oleaceae; antioxidative activity; DPPH scavenging activity; H₂O₂ scavenging ability; phenolic antioxidant

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