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Molecules 2012, 17(9), 10708-10715; doi:10.3390/molecules170910708

An Improved Synthesis of 1,2-Diarylethanols under Conventional Heating and Ultrasound Irradiation

College of Science, Northwest A&F University, Yangling 712100, Shaanxi, China
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Received: 7 August 2012 / Revised: 28 August 2012 / Accepted: 3 September 2012 / Published: 7 September 2012
(This article belongs to the Section Organic Synthesis)
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Abstract

A simple and efficient synthesis of 1,2-diarylethanols has been developed. The procedure involved the reaction between a variety of toluene derivatives and aryl aldehydes under conventional heating and ultrasound irradiation. This procedure possesses several advantages such as operational simplicity, high yield, safety and environment benignancy. Ultrasound was proved to be very helpful to the reaction, markedly improving the yield and the reaction rate.
Keywords: 1,2-diarylethanols; ultrasonic-assisted organic synthesis; 2-nitrotoulene 1,2-diarylethanols; ultrasonic-assisted organic synthesis; 2-nitrotoulene
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Gao, D.-M.; Ma, W.-L.; Li, T.-R.; Huang, L.-Z.; Du, Z.-T. An Improved Synthesis of 1,2-Diarylethanols under Conventional Heating and Ultrasound Irradiation. Molecules 2012, 17, 10708-10715.

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