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Molecules 2012, 17(9), 10614-10651; doi:10.3390/molecules170910614

Advances in the Chemical Analysis and Biological Activities of Chuanxiong

Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210046, Jiangsu, China
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Received: 28 June 2012 / Revised: 19 August 2012 / Accepted: 20 August 2012 / Published: 6 September 2012
(This article belongs to the Section Natural Products)
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Abstract

Chuanxiong Rhizoma (Chuan-Xiong, CX), the dried rhizome of Ligusticum chuanxiong Hort. (Umbelliferae), is one of the most popular plant medicines in the World. Modern research indicates that organic acids, phthalides, alkaloids, polysaccharides, ceramides and cerebrosides are main components responsible for the bioactivities and properties of CX. Because of its complex constituents, multidisciplinary techniques are needed to validate the analytical methods that support CX’s use worldwide. In the past two decades, rapid development of technology has advanced many aspects of CX research. The aim of this review is to illustrate the recent advances in the chemical analysis and biological activities of CX, and to highlight new applications and challenges. Emphasis is placed on recent trends and emerging techniques.
Keywords: Chuanxiong; organic acids; phthalides; alkaloids; polysaccharides; ceramides; cerebrosides Chuanxiong; organic acids; phthalides; alkaloids; polysaccharides; ceramides; cerebrosides
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Li, W.; Tang, Y.; Chen, Y.; Duan, J.-A. Advances in the Chemical Analysis and Biological Activities of Chuanxiong. Molecules 2012, 17, 10614-10651.

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