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Molecules 2012, 17(9), 10292-10305; doi:10.3390/molecules170910292

Cassia spectabilis (DC) Irwin et Barn: A Promising Traditional Herb in Health Improvement

1
Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia
2
School of Biological Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia
3
Faculty of Medicine and Health Sciences, Universiti Sultan Zainal Abidin, Kota Kampus, 20400 Kuala Terengganu, Terengganu, Malaysia
4
Dental Research and Training Unit, and Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, Kuala Lumpur 50603, Malaysia
5
Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Jalan Bedong Semeling, Batu 3½, Bukit Air Nasi, Bedong 08100, Kedah, Malaysia
*
Authors to whom correspondence should be addressed.
Received: 18 June 2012 / Revised: 18 August 2012 / Accepted: 20 August 2012 / Published: 29 August 2012
(This article belongs to the Section Natural Products)
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Abstract

The genus Cassia, comprising about 600 species widely distributed worldwide is well known for its diverse biological and pharmacological properties. Cassia spectabilis (sin Senna spectabilis) (DC) Irwin et Barn (Fabaceae) is widely grown as an ornamental plant in tropical and subtropical areas. C. spectabilis has been commonly used in traditional medicine for many years. Information in the biomedical literature has indicated the presence of a variety of medicinally-important chemical constituents in C. spectabilis. Pharmacological studies by various groups of investigators have shown that C. spectabilis possesses significant biological activity, such as antibacterial, antibiofilm, antifungal and antioxidant properties. Beside this, toxicity studies of this plant have revealed no toxic effect on mice. In view of the immense medicinal importance of C. spectabilis, this review aimed at compiling all currently available information on C. spectabilis’s botany, phytochemistry, pharmacology, and mechanism of actions, toxicology and its ethnomedicinal uses.
Keywords: Cassia spectabilis; pharmacological properties; ethnomedicinal uses; phytochemistry Cassia spectabilis; pharmacological properties; ethnomedicinal uses; phytochemistry
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Jothy, S.L.; Torey, A.; Darah, I.; Choong, Y.S.; Saravanan, D.; Chen, Y.; Latha, L.Y.; Deivanai, S.; Sasidharan, S. Cassia spectabilis (DC) Irwin et Barn: A Promising Traditional Herb in Health Improvement. Molecules 2012, 17, 10292-10305.

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