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Molecules 2012, 17(9), 10276-10291; doi:10.3390/molecules170910276
Article

Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus aureus

1
, 1
, 2
 and 1,*
1 Medical and Sanitary Microbiology Department, Medical University of Lodz, Hallera Sq. 1, Lodz 90-647, Poland 2 Institute of General Food Chemistry, Lodz University of Technology, Stefanowskiego Str., 4/10, Lodz 90-924, Poland
* Author to whom correspondence should be addressed.
Received: 28 June 2012 / Revised: 12 August 2012 / Accepted: 14 August 2012 / Published: 28 August 2012
(This article belongs to the Special Issue Macromolecules Applied to Pharmaceutics)
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Abstract

The aim of this work was to investigate the antibacterial properties of geranium oil obtained from Pelargonium graveolens Ait. (family Geraniaceae), against one standard S. aureus strain ATCC 433000 and seventy clinical S. aureus strains. The agar dilution method was used for assessment of bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment showed that the oil from P. graveolens has strong activity against all of the clinical S. aureus isolates—including multidrug resistant strains, MRSA strains and MLSB-positive strains—exhibiting MIC values of 0.25–2.50 μL/mL.
Keywords: antibacterial activity; geranium oil; MIC; multidrug resistant strains; Staphylococcus aureus antibacterial activity; geranium oil; MIC; multidrug resistant strains; Staphylococcus aureus
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bigos, M.; Wasiela, M.; Kalemba, D.; Sienkiewicz, M. Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus aureus. Molecules 2012, 17, 10276-10291.

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