Next Article in Journal
Alkaloids Isolated from the Lateral Root of Aconitum carmichaelii
Previous Article in Journal
Anti-metastatic Semi-synthetic Sulfated Maltotriose C-C Linked Dimers. Synthesis and Characterisation
Article Menu

Export Article

Open AccessArticle
Molecules 2012, 17(8), 9931-9938; https://doi.org/10.3390/molecules17089931

The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside

1
Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima 890-0065, Japan
2
Division of Hematology and Immunology, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan
3
Priority Organization for Innovation and Excellence, Kumamoto University, 5-1 Oe-Honmachi, Kumamoto 860-8555, Japan
*
Author to whom correspondence should be addressed.
Received: 12 June 2012 / Revised: 7 August 2012 / Accepted: 8 August 2012 / Published: 17 August 2012
(This article belongs to the Section Natural Products Chemistry)
View Full-Text   |   Download PDF [693 KB, uploaded 18 June 2014]   |  

Abstract

Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of Hyptis verticillata. View Full-Text
Keywords: ATL; bioassay-guided isolation; S1T; growth inhibitor; lignan; NMR; structure ATL; bioassay-guided isolation; S1T; growth inhibitor; lignan; NMR; structure
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Hamada, T.; White, Y.; Nakashima, M.; Oiso, Y.; Fujita, M.J.; Okamura, H.; Iwagawa, T.; Arima, N. The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside. Molecules 2012, 17, 9931-9938.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top