Next Article in Journal
A New Natural Lactone from Dimocarpus longan Lour. Seeds
Previous Article in Journal
Improvement in the Water Retention Characteristics of Sandy Loam Soil Using a Newly Synthesized Poly(acrylamide-co-acrylic Acid)/AlZnFe2O4 Superabsorbent Hydrogel Nanocomposite Material
Article Menu

Export Article

Open AccessArticle
Molecules 2012, 17(8), 9413-9420; doi:10.3390/molecules17089413

N-Substituted 5-Chloro-6-phenylpyridazin-3(2H)-ones: Synthesis, Insecticidal Activity Against Plutella xylostella (L.) and SAR Study

State Key Laboratory Breeding Base of Green Pesticides and Agricultural Bioengineering, Key Laboratory of Green Pesticides and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China
*
Author to whom correspondence should be addressed.
Received: 5 July 2012 / Revised: 27 July 2012 / Accepted: 30 July 2012 / Published: 6 August 2012
View Full-Text   |   Download PDF [235 KB, uploaded 18 June 2014]   |  

Abstract

A series of N-substituted 5-chloro-6-phenylpyridazin-3(2H)-one derivatives were synthesized based on our previous work; all compounds were characterized by spectral data and tested for in vitro insecticidal activity against Plutella xylostella. The results showed that the synthesized pyridazin-3(2H)-one compounds possessed good insecticidal activities, especially the compounds 4b, 4d, and 4h which showed > 90% activity at 100 mg/L. The structure-activity relationships (SAR) for these compounds were also discussed.
Keywords: pridazin-3(2H)-one; synthesis; insecticidal activity; SAR study; Plutella xylostella pridazin-3(2H)-one; synthesis; insecticidal activity; SAR study; Plutella xylostella
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Wu, J.; Kang, S.; Yuan, Q.; Luo, L.; Ma, J.; Shi, Q.; Yang, S. N-Substituted 5-Chloro-6-phenylpyridazin-3(2H)-ones: Synthesis, Insecticidal Activity Against Plutella xylostella (L.) and SAR Study. Molecules 2012, 17, 9413-9420.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top