Molecules 2012, 17(5), 5713-5723; doi:10.3390/molecules17055713
Article

Antifungal Activities of New Coumarins

1,2,* email, 1 and 1
Received: 31 March 2012; in revised form: 12 April 2012 / Accepted: 20 April 2012 / Published: 14 May 2012
(This article belongs to the Section Medicinal Chemistry)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Newly synthesized coumarins 4-((5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)-methoxy)-2H-chromen-2-one and 4-((5-(phenylamino)-1,3,4-thiadiazol-2-yl)-methoxy)-2H-chromen-2-one were tested against selected types of fungi and showed significant activities. DFT calculations of the synthesized coumarins were performed using molecular structures with optimized geometries. Molecular orbital calculations provide a detailed description of the orbitals, including spatial characteristics, nodal patterns, and the contributions of individual atoms.
Keywords: antifungal; 4-aminoantipyrine; benzyl bromide; coumarins; DFT; ethyl bromoacetate; 4-hydroxycoumarin
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MDPI and ACS Style

Al-Amiery, A.A.; Kadhum, A.A.H.; Mohamad, A.B. Antifungal Activities of New Coumarins. Molecules 2012, 17, 5713-5723.

AMA Style

Al-Amiery AA, Kadhum AAH, Mohamad AB. Antifungal Activities of New Coumarins. Molecules. 2012; 17(5):5713-5723.

Chicago/Turabian Style

Al-Amiery, Ahmed A.; Kadhum, Abdul Amir Hassan; Mohamad, Abu Bakar. 2012. "Antifungal Activities of New Coumarins." Molecules 17, no. 5: 5713-5723.

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