Next Article in Journal
Parallel Synthesis of Peptide-Like Macrocycles Containing Imidazole-4,5-dicarboxylic Acid
Previous Article in Journal
A Convenient Synthesis of Triflate Anion Ionic Liquids and Their Properties
Article Menu

Article Versions

Export Article

Open AccessCommunication
Molecules 2012, 17(5), 5339-5345; doi:10.3390/molecules17055339

Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water

School of Materials and Chemical Engineering, Anhui University of Architecture, Hefei 230601, China
*
Author to whom correspondence should be addressed.
Received: 13 March 2012 / Revised: 24 April 2012 / Accepted: 28 April 2012 / Published: 7 May 2012
Download PDF [177 KB, uploaded 18 June 2014]

Abstract

Acridinediones were synthesized by the one-pot Hantzsch condensation of an aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione, and aniline/4-methylaniline in refluxing water. This method has then been extended to the four-component reaction of an aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione, ethyl acetoacetate and ammonium acetate for the synthesis of polyhydroquinoline derivatives. This is an environmentally friendly and efficient procedure providing good to excellent yields.
Keywords: acridinedione; polyhydroquinoline; one-pot reaction; water acridinedione; polyhydroquinoline; one-pot reaction; water
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Xia, J.-J.; Zhang, K.-H. Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water. Molecules 2012, 17, 5339-5345.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top