Molecules 2012, 17(5), 5339-5345; doi:10.3390/molecules17055339
Communication

Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water

School of Materials and Chemical Engineering, Anhui University of Architecture, Hefei 230601, China
* Author to whom correspondence should be addressed.
Received: 13 March 2012; in revised form: 24 April 2012 / Accepted: 28 April 2012 / Published: 7 May 2012
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Abstract: Acridinediones were synthesized by the one-pot Hantzsch condensation of an aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione, and aniline/4-methylaniline in refluxing water. This method has then been extended to the four-component reaction of an aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione, ethyl acetoacetate and ammonium acetate for the synthesis of polyhydroquinoline derivatives. This is an environmentally friendly and efficient procedure providing good to excellent yields.
Keywords: acridinedione; polyhydroquinoline; one-pot reaction; water

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MDPI and ACS Style

Xia, J.-J.; Zhang, K.-H. Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water. Molecules 2012, 17, 5339-5345.

AMA Style

Xia J-J, Zhang K-H. Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water. Molecules. 2012; 17(5):5339-5345.

Chicago/Turabian Style

Xia, Jing-Jing; Zhang, Ke-Hua. 2012. "Synthesis of N-substituted Acridinediones and Polyhydroquinoline Derivatives in Refluxing Water." Molecules 17, no. 5: 5339-5345.

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