Next Article in Journal
Total Synthesis and Antidepressant Activities of Laetispicine and Its Derivatives
Previous Article in Journal
Supramolecular Photodimerization of Coumarins
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2012, 17(2), 1419-1424; doi:10.3390/molecules17021419

A New Iridoid Glycoside from the Roots of Dipsacus asper

State Key Laboratory of Natural Products and Functions, China Pharmaceutical University, Ministry of Education, 24 Tong Jia Xiang, Nanjing 210009, China
*
Author to whom correspondence should be addressed.
Received: 13 January 2012 / Revised: 21 January 2012 / Accepted: 30 January 2012 / Published: 3 February 2012
(This article belongs to the Section Natural Products)
Download PDF [223 KB, uploaded 18 June 2014]   |  

Abstract

A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4′,4′′-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ25–35 induced cell death in PC12 cells.
Keywords: Dipsacus asper; iridoid glycoside; loganic acid ethyl ester; neuroprotective effect; Dipsaceae Dipsacus asper; iridoid glycoside; loganic acid ethyl ester; neuroprotective effect; Dipsaceae
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Ji, D.; Zhang, C.; Li, J.; Yang, H.; Shen, J.; Yang, Z. A New Iridoid Glycoside from the Roots of Dipsacus asper. Molecules 2012, 17, 1419-1424.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top