This article is
- freely available
Recent Developments in the Reformatsky-Claisen Rearrangement
Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan
* Author to whom correspondence should be addressed.
Received: 8 November 2012; in revised form: 21 November 2012 / Accepted: 27 November 2012 / Published: 30 November 2012
Abstract: The rearrangement of allyl a-bromoacetates with Zn dust is known as the Reformatsky-Claisen rearrangement. Whereas the Ireland-Claisen rearrangement has been widely used in the synthesis of a diverse range of natural products, the Zn-mediated Reformatsky-Claisen rearrangement has not been utilized so often. In this article, we will provide an overview of recent advances in the Reformatsky-Claisen rearrangement field, including the In-mediated Reformatsky-Claisen rearrangement we have recently developed.
Keywords: Reformatsky-Claisen rearrangement; Reformatsky reaction; Claisen rearrangement; zinc; indium
Article StatisticsClick here to load and display the download statistics.
Notes: Multiple requests from the same IP address are counted as one view.
Cite This Article
MDPI and ACS Style
Ishihara, J.; Hatakeyama, S. Recent Developments in the Reformatsky-Claisen Rearrangement. Molecules 2012, 17, 14249-14259.
Ishihara J, Hatakeyama S. Recent Developments in the Reformatsky-Claisen Rearrangement. Molecules. 2012; 17(12):14249-14259.
Ishihara, Jun; Hatakeyama, Susumi. 2012. "Recent Developments in the Reformatsky-Claisen Rearrangement." Molecules 17, no. 12: 14249-14259.