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Molecules 2012, 17(12), 14249-14259; doi:10.3390/molecules171214249
Article

Recent Developments in the Reformatsky-Claisen Rearrangement

*  and
Received: 8 November 2012 / Revised: 21 November 2012 / Accepted: 27 November 2012 / Published: 30 November 2012
(This article belongs to the Special Issue Claisen Rearrangement)
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Abstract

The rearrangement of allyl a-bromoacetates with Zn dust is known as the Reformatsky-Claisen rearrangement. Whereas the Ireland-Claisen rearrangement has been widely used in the synthesis of a diverse range of natural products, the Zn-mediated Reformatsky-Claisen rearrangement has not been utilized so often. In this article, we will provide an overview of recent advances in the Reformatsky-Claisen rearrangement field, including the In-mediated Reformatsky-Claisen rearrangement we have recently developed.
Keywords: Reformatsky-Claisen rearrangement; Reformatsky reaction; Claisen rearrangement; zinc; indium Reformatsky-Claisen rearrangement; Reformatsky reaction; Claisen rearrangement; zinc; indium
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ishihara, J.; Hatakeyama, S. Recent Developments in the Reformatsky-Claisen Rearrangement. Molecules 2012, 17, 14249-14259.

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