Isolation, Identification and Antimicrobial Activities of Two Secondary Metabolites of Talaromyces verruculosus
Abstract
:1. Introduction
2. Results and Discussion
2.1. Isolation and Structural Identification
2.2. Bioactivity
Compound | Growth inhibition (%, mean ± SD) | MIC (µg mL−1) | ||||
---|---|---|---|---|---|---|
A. solani | V. mali | C. lunata | B. berengeriana | S. aureus | E. coli | |
1 | 92.6 ± 2.1 | 97.3 ± 3.3 | 87.2 ± 2.8 | 94.9 ± 3.9 | 2.5 | 5.0 |
2 | N a (16.3 ± 5.4) b | N (21.3 ± 4.6) | N (25.6 ± 5.4) | N (19.7 ± 3.8) | >100 | >100 |
Thiabendazole | 54.7 ± 2.6 | 100 ± 0.0 | 51.5 ± 4.1 | 92.8 ± 3.7 | ― | ― |
Ceftriaxone sodium | ― | ― | ― | ― | 0.625 | 0.625 |
3. Experimental
3.1. General
3.2. Plant and Fungal Strain Materials
3.3. Fermentation
3.4. Extraction and Isolation
3.5. Antibacterial Assay
3.6. Antifungal Assay
4. Conclusions
Acknowledgments
- Sample Availability: Samples of the compounds 1 and 2 are available from the authors.
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Miao, F.; Yang, R.; Chen, D.-D.; Wang, Y.; Qin, B.-F.; Yang, X.-J.; Zhou, L. Isolation, Identification and Antimicrobial Activities of Two Secondary Metabolites of Talaromyces verruculosus. Molecules 2012, 17, 14091-14098. https://doi.org/10.3390/molecules171214091
Miao F, Yang R, Chen D-D, Wang Y, Qin B-F, Yang X-J, Zhou L. Isolation, Identification and Antimicrobial Activities of Two Secondary Metabolites of Talaromyces verruculosus. Molecules. 2012; 17(12):14091-14098. https://doi.org/10.3390/molecules171214091
Chicago/Turabian StyleMiao, Fang, Rui Yang, Dong-Dong Chen, Ying Wang, Bao-Fu Qin, Xin-Juan Yang, and Le Zhou. 2012. "Isolation, Identification and Antimicrobial Activities of Two Secondary Metabolites of Talaromyces verruculosus" Molecules 17, no. 12: 14091-14098. https://doi.org/10.3390/molecules171214091