Molecules 2012, 17(10), 11303-11314; doi:10.3390/molecules171011303
Article

Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities

Xiangjie Meng 1 , Ziling Mao 1 , Jingfeng Lou 1 , Liang Xu 1 , Lingyun Zhong 1 , Youliang Peng 1 , Ligang Zhou 1,* email and Mingan Wang 2,* email
1 College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China 2 College of Science, China Agricultural University, Beijing 100193, China
* Authors to whom correspondence should be addressed.
Received: 16 August 2012; in revised form: 4 September 2012 / Accepted: 19 September 2012 / Published: 25 September 2012
(This article belongs to the Section Natural Products)
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Abstract: The endophytic fungus Hyalodendriella sp. Ponipodef12 was isolated from the hybrid ‘Neva’ of Populus deltoides Marsh × P. nigra L. In this study, four benzopyranones were isolated from the ethyl acetate extract of Hyalodendriella sp. Ponipodef12, and identified as palmariol B (1), 4-hydroxymellein (2), alternariol 9-methyl ether (3), and botrallin (4) by means of physicochemical and spectroscopic analysis. All the compounds were evaluated for their antibacterial, antifungal, antinematodal and acetylcholinesterase inhibitory activities. 4-Hydroxymellein (2) exhibited stronger antibacterial activity than the other compounds. Palmariol B (1) showed stronger antimicrobial, antinematodal and acetylcholinesterase inhibitory activities than alternariol 9-methyl ether (3) which indicated that the chlorine substitution at position 2 may contribute to its bioactivity. The results indicate the potential of this endophytic fungus as a source of bioactive benzopyranones.
Keywords: poplar hybrid ‘Neva’ endophytic fungus; Hyalodendriella sp. Ponipodef12; benzopyranones; palmariol B; 4-hydroxymellein; alternariol 9-methyl ether; botrallin; bioactivities

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Cite This Article

MDPI and ACS Style

Meng, X.; Mao, Z.; Lou, J.; Xu, L.; Zhong, L.; Peng, Y.; Zhou, L.; Wang, M. Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities. Molecules 2012, 17, 11303-11314.

AMA Style

Meng X, Mao Z, Lou J, Xu L, Zhong L, Peng Y, Zhou L, Wang M. Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities. Molecules. 2012; 17(10):11303-11314.

Chicago/Turabian Style

Meng, Xiangjie; Mao, Ziling; Lou, Jingfeng; Xu, Liang; Zhong, Lingyun; Peng, Youliang; Zhou, Ligang; Wang, Mingan. 2012. "Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities." Molecules 17, no. 10: 11303-11314.

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