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Molecules 2012, 17(1), 762-785; doi:10.3390/molecules17010762

Anti-bacterial Treatment of Polyethylene by Cold Plasma for Medical Purposes

1, 1,* , 2, 1, 3, 3, 3, 4, 4, 1, 5 and 6
1 Polymer Institute, Slovak Academy of Sciences, Dúbravská cesta 9, 845 41 Bratislava 45, Slovakia 2 Centre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Nad Ovčírnou 3685, 760 01 Zlín, Czech Republic 3 Faculty of Wood Sciences and Technology, Technical University in Zvolen, T.G. Masaryka 2117/24, 960 53 Zvolen, Slovakia 4 Plasma Laboratory, Department of Surface Engineering, Jožef Stefan Institute, Jamova cesta 39, SI-1000 Ljubljana, Slovenia 5 Institute of Macromolecular Chemistry AS CR, v. v. i, Heyrovsky Sq. 2, 162 06 Prague 6, Czech Republic 6 Polymer Centre, Faculty of Technology, Tomas Bata University in Zlín, T.G.M Sq. 275, 762 72 Zlín, Czech Republic
* Author to whom correspondence should be addressed.
Received: 16 November 2011 / Revised: 9 January 2012 / Accepted: 10 January 2012 / Published: 13 January 2012
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Polyethylene (PE) is one of the most widely used polymers in many industrial applications. Biomedical uses seem to be attractive, with increasing interest. However, PE it prone to infections and its additional surface treatment is indispensable. An increase in resistance to infections can be achieved by treating PE surfaces with substances containing antibacterial groups such as triclosan (5-Chloro-2-(2,4-dichlorophenoxy)phenol) and chlorhexidine (1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide]). This work has examined the impact of selected antibacterial substances immobilized on low-density polyethylene (LDPE) via polyacrylic acid (PAA) grafted on LDPE by low-temperature barrier discharge plasma. This LDPE surface treatment led to inhibition of Escherichia coli and Staphylococcus aureus adhesion; the first causes intestinal disease, peritonitis, mastitis, pneumonia, septicemia, the latter is the reason for wound and urinary tract infections.
Keywords: polyethylene; grafting; plasma treatment; immobilization; triclosan; chlorhexidine; acrylic acid polyethylene; grafting; plasma treatment; immobilization; triclosan; chlorhexidine; acrylic acid
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Popelka, A.; Novák, I.; Lehocký, M.; Chodák, I.; Sedliačik, J.; Gajtanska, M.; Sedliačiková, M.; Vesel, A.; Junkar, I.; Kleinová, A.; Špírková, M.; Bílek, F. Anti-bacterial Treatment of Polyethylene by Cold Plasma for Medical Purposes. Molecules 2012, 17, 762-785.

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