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Molecules 2012, 17(1), 657-663; doi:10.3390/molecules17010657
Article

A New Prenylated Flavanone from Derris trifoliata Lour.

1,†
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Received: 30 October 2011; in revised form: 26 December 2011 / Accepted: 27 December 2011 / Published: 11 January 2012
(This article belongs to the Section Metabolites)
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Abstract: A new flavanone, 4′,5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy-6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-methoxyflavanone. 7a-O-Methylelliptonol was isolated for the first time from the genus Derris. Their structures were characterized on the basis of spectral data. Eight of the isolated compounds were found to be significantly toxic to brine shrimp (LC50 range 0.06–9.95 μg/mL). The new compound showed weak toxicity (LC50 = 211.31 μg/mL).
Keywords: Derris trifoliate; aerial part; prenylated flavanone; rotenoids; brine shrimp toxicity Derris trifoliate; aerial part; prenylated flavanone; rotenoids; brine shrimp toxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Jiang, C.; Liu, S.; He, W.; Luo, X.; Zhang, S.; Xiao, Z.; Qiu, X.; Yin, H. A New Prenylated Flavanone from Derris trifoliata Lour.. Molecules 2012, 17, 657-663.

AMA Style

Jiang C, Liu S, He W, Luo X, Zhang S, Xiao Z, Qiu X, Yin H. A New Prenylated Flavanone from Derris trifoliata Lour.. Molecules. 2012; 17(1):657-663.

Chicago/Turabian Style

Jiang, Cheng; Liu, Shengzi; He, Weihong; Luo, Xiongming; Zhang, Si; Xiao, Zhihui; Qiu, Ximin; Yin, Hao. 2012. "A New Prenylated Flavanone from Derris trifoliata Lour.." Molecules 17, no. 1: 657-663.


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