Next Article in Journal
Neonaucline, a New Indole Alkaloid from the Leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae)
Previous Article in Journal
Practical Synthesis of Hydroxychromenes and Evaluation of Their Biological Activity
Article Menu

Article Versions

Export Article

Open AccessReview
Molecules 2012, 17(1), 248-266; doi:10.3390/molecules17010248

Oligosaccharides Might Contribute to the Antidiabetic Effect of Honey: A Review of the Literature

Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
*
Author to whom correspondence should be addressed.
Received: 26 October 2011 / Revised: 15 December 2011 / Accepted: 16 December 2011 / Published: 28 December 2011
Download PDF [216 KB, uploaded 18 June 2014]

Abstract

Evidence shows that honey improves glycemic control in diabetes mellitus. Besides its hypoglycemic effect, studies indicate that honey ameliorates lipid abnormalities in rats and humans with diabetes. The majority of these studies do not examine the mechanisms by which honey ameliorates glycemic and/or lipid derangements. The gut microbiota is now recognized for its ability to increase energy harvest from the diet and alter lipid metabolism of the host. Recently available data implicate a causal role of these gut microbes in the pathophysiology of obesity, insulin resistance, and diabetes mellitus. In this review, we present some of the latest findings linking gut microbiota to pathogenesis of obesity, insulin resistance, and diabetes mellitus. The review also underlines data that demonstrate the beneficial effects of oligosaccharides on various abnormalities commonly associated with these disorders. Based on the similarities of some of these findings with those of honey, together with the evidence that honey contains oligosaccharides, we hypothesize that oligosaccharides present in honey might contribute to the antidiabetic and other health-related beneficial effects of honey. We anticipate that the possibility of oligosaccharides in honey contributing to the antidiabetic and other health-related effects of honey will stimulate a renewed research interest in this field.
Keywords: prebiotics; oligosaccharides; honey; hypoglycemic; anti-diabetic; microbiota; body weight; food intake prebiotics; oligosaccharides; honey; hypoglycemic; anti-diabetic; microbiota; body weight; food intake
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Erejuwa, O.O.; Sulaiman, S.A.; Wahab, M.S.A. Oligosaccharides Might Contribute to the Antidiabetic Effect of Honey: A Review of the Literature. Molecules 2012, 17, 248-266.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top