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Molecules 2012, 17(1), 151-162; doi:10.3390/molecules17010151
Article

Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones

, , ,  and *
Received: 25 October 2011; in revised form: 21 December 2011 / Accepted: 22 December 2011 / Published: 27 December 2011
(This article belongs to the Section Organic Synthesis)
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Abstract: We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.
Keywords: 1,3-amino alcohols; 3-aminocyclohexanols; β-enaminoketones; reduction of β-enaminoketones 1,3-amino alcohols; 3-aminocyclohexanols; β-enaminoketones; reduction of β-enaminoketones
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Balbás, I.M.; Mendoza, B.E.D.; Fernández-Zertuche, M.; Ordoñez, M.; Linzaga-Elizalde, I. Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones. Molecules 2012, 17, 151-162.

AMA Style

Balbás IM, Mendoza BED, Fernández-Zertuche M, Ordoñez M, Linzaga-Elizalde I. Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones. Molecules. 2012; 17(1):151-162.

Chicago/Turabian Style

Balbás, Iris Montoya; Mendoza, Blanca Eda Domínguez; Fernández-Zertuche, Mario; Ordoñez, Mario; Linzaga-Elizalde, Irma. 2012. "Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones." Molecules 17, no. 1: 151-162.


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