Molecules 2012, 17(1), 151-162; doi:10.3390/molecules17010151
Article

Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones

Iris Montoya Balbás, Blanca Eda Domínguez Mendoza, Mario Fernández-Zertuche, Mario Ordoñez and Irma Linzaga-Elizalde* email
Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Cuernavaca, Mor., CP 62209, Mexico
* Author to whom correspondence should be addressed.
Received: 25 October 2011; in revised form: 21 December 2011 / Accepted: 22 December 2011 / Published: 27 December 2011
(This article belongs to the Section Organic Synthesis)
PDF Full-text Download PDF Full-Text [337 KB, uploaded 27 December 2011 09:32 CET]
Abstract: We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.
Keywords: 1,3-amino alcohols; 3-aminocyclohexanols; β-enaminoketones; reduction of β-enaminoketones

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Balbás, I.M.; Mendoza, B.E.D.; Fernández-Zertuche, M.; Ordoñez, M.; Linzaga-Elizalde, I. Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones. Molecules 2012, 17, 151-162.

AMA Style

Balbás IM, Mendoza BED, Fernández-Zertuche M, Ordoñez M, Linzaga-Elizalde I. Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones. Molecules. 2012; 17(1):151-162.

Chicago/Turabian Style

Balbás, Iris Montoya; Mendoza, Blanca Eda Domínguez; Fernández-Zertuche, Mario; Ordoñez, Mario; Linzaga-Elizalde, Irma. 2012. "Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones." Molecules 17, no. 1: 151-162.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert