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Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
* Author to whom correspondence should be addressed.
Received: 22 June 2011; in revised form: 15 August 2011 / Accepted: 16 August 2011 / Published: 30 August 2011
Abstract: In this paper, microwave-assisted extraction (MAE) of oxymatrine from Sophora flavescens were studied by HPLC-photodiode array detection. Effects of several experimental parameters, such as concentration of extraction solvent, ratio of liquid to material, microwave power, extraction temperature, and extraction time on the extraction efficiencies of oxymatrine were evaluated. The optimal extraction conditions were 60% ethanol, a 20:1 (v/v) ratio of liquid to material and extraction for 10 min at 50 °C under 500 W microwave irradiation. Under the optimum conditions, the yield of oxymatrine was 14.37 mg/g. The crude extract obtained could be used as either a component of some complex traditional medicines or for further isolation and purification of bioactive compounds. The results, which indicated that MAE is a very useful tool for the extraction of important phytochemicals from plant materials, should prove helpful for the full utilization of Sophora flavescens.
Keywords: microwave; extraction; oxymatrine; Sophora flavescens
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MDPI and ACS Style
Xia, E.-Q.; Cui, B.; Xu, X.-R.; Song, Y.; Ai, X.-X.; Li, H.-B. Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens. Molecules 2011, 16, 7391-7400.
Xia E-Q, Cui B, Xu X-R, Song Y, Ai X-X, Li H-B. Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens. Molecules. 2011; 16(9):7391-7400.
Xia, En-Qin; Cui, Bo; Xu, Xiang-Rong; Song, Yang; Ai, Xu-Xia; Li, Hua-Bin. 2011. "Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens." Molecules 16, no. 9: 7391-7400.