Molecules 2011, 16(9), 7391-7400; doi:10.3390/molecules16097391

Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens

1email, 1email, 2email, 1email, 1email and 1,* email
Received: 22 June 2011; in revised form: 15 August 2011 / Accepted: 16 August 2011 / Published: 30 August 2011
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: In this paper, microwave-assisted extraction (MAE) of oxymatrine from Sophora flavescens were studied by HPLC-photodiode array detection. Effects of several experimental parameters, such as concentration of extraction solvent, ratio of liquid to material, microwave power, extraction temperature, and extraction time on the extraction efficiencies of oxymatrine were evaluated. The optimal extraction conditions were 60% ethanol, a 20:1 (v/v) ratio of liquid to material and extraction for 10 min at 50 °C under 500 W microwave irradiation. Under the optimum conditions, the yield of oxymatrine was 14.37 mg/g. The crude extract obtained could be used as either a component of some complex traditional medicines or for further isolation and purification of bioactive compounds. The results, which indicated that MAE is a very useful tool for the extraction of important phytochemicals from plant materials, should prove helpful for the full utilization of Sophora flavescens.
Keywords: microwave; extraction; oxymatrine; Sophora flavescens
PDF Full-text Download PDF Full-Text [381 KB, uploaded 18 June 2014 19:40 CEST]

Export to BibTeX |

MDPI and ACS Style

Xia, E.-Q.; Cui, B.; Xu, X.-R.; Song, Y.; Ai, X.-X.; Li, H.-B. Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens. Molecules 2011, 16, 7391-7400.

AMA Style

Xia E-Q, Cui B, Xu X-R, Song Y, Ai X-X, Li H-B. Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens. Molecules. 2011; 16(9):7391-7400.

Chicago/Turabian Style

Xia, En-Qin; Cui, Bo; Xu, Xiang-Rong; Song, Yang; Ai, Xu-Xia; Li, Hua-Bin. 2011. "Microwave-Assisted Extraction of Oxymatrine from Sophora flavescens." Molecules 16, no. 9: 7391-7400.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert