Molecules 2011, 16(8), 6833-6843; doi:10.3390/molecules16086833
Article

The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

1 Department of Chemical and Processing Engineering, Faculty of Engineering and Built Environment, University of Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia 2 Biotechnology Division, Applied Science Department, University of Technology, Baghdad 10066, Iraq
* Author to whom correspondence should be addressed.
Received: 11 July 2011; in revised form: 22 July 2011 / Accepted: 1 August 2011 / Published: 10 August 2011
(This article belongs to the Section Organic Synthesis)
PDF Full-text Download PDF Full-Text [522 KB, uploaded 10 August 2011 13:13 CEST]
Abstract: New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, 1H-NMR and 13C-NMR).
Keywords: coumarin; ethyl bromoacetate; phosphorous oxychloride; 1,3,4-thiadiazole; thiosemicarbazide; umbelliferone

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Al-Amiery, A.A.; Musa, A.Y.; Kadhum, A.A.H.; Mohamad, A.B. The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds. Molecules 2011, 16, 6833-6843.

AMA Style

Al-Amiery AA, Musa AY, Kadhum AAH, Mohamad AB. The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds. Molecules. 2011; 16(8):6833-6843.

Chicago/Turabian Style

Al-Amiery, Ahmed A.; Musa, Ahmed Y.; Kadhum, Abdul Amir H.; Mohamad, Abu Bakar. 2011. "The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds." Molecules 16, no. 8: 6833-6843.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert