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Lianqiaoxinoside B, a Novel Caffeoyl Phenylethanoid Glycoside from Forsythia suspensa
Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin 150040, China
* Author to whom correspondence should be addressed.
Received: 25 May 2011; in revised form: 21 June 2011 / Accepted: 22 June 2011 / Published: 4 July 2011
Abstract: Chemical investigation of the 70% ethanol extract of the unripe fruits of Forsythia suspensa resulted in the isolation of a novel caffeoyl phenylethanoid glycoside, lianqiaoxinoside B, together with the known compound forsythoside H. The new compound was elucidated to be 1'',2''-[β-(3,4,-dihydroxylphenyl)-α,β-dioxoethanol]-3''-O-caffeoyl-O-α-rhamnopyranosyl-(1→6)-O-β-glucopyranoside by extensive spectroscopic and chemical studies. Lianqiaoxinoside B and forsythoside H showed strong antioxidant and antimicrobial activities in vitro by the 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonate (ABTS) radical-scavenging assay and plate method. This study can be further extended to exploit for the possible application of caffeoyl phenylethanoid glycosides as the alternative antioxidants and antimicrobial agents of natural origin.
Keywords: Forsythia suspensa; caffeoyl phenylethanoid glycoside; antioxidant and antimicrobial activities
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Kuang, H.-X.; Xia, Y.-G.; Liang, J.; Yang, B.-Y.; Wang, Q.-H. Lianqiaoxinoside B, a Novel Caffeoyl Phenylethanoid Glycoside from Forsythia suspensa. Molecules 2011, 16, 5674-5681.
Kuang H-X, Xia Y-G, Liang J, Yang B-Y, Wang Q-H. Lianqiaoxinoside B, a Novel Caffeoyl Phenylethanoid Glycoside from Forsythia suspensa. Molecules. 2011; 16(7):5674-5681.
Kuang, Hai-Xue; Xia, Yong-Gang; Liang, Jun; Yang, Bing-You; Wang, Qiu-Hong. 2011. "Lianqiaoxinoside B, a Novel Caffeoyl Phenylethanoid Glycoside from Forsythia suspensa." Molecules 16, no. 7: 5674-5681.