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Molecules 2011, 16(6), 4719-4727; doi:10.3390/molecules16064719
Article

Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093

1,†,* , 1,†, 1, 1, 1, 2, 1 and 1,*
1 Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), Hsinchu 300, Taiwan 2 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University (KMU), Kaohsiung 807, Taiwan These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 4 May 2011 / Revised: 30 May 2011 / Accepted: 31 May 2011 / Published: 7 June 2011
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Abstract

Four new pyridine derivatives, monasnicotinates A–D (14) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effects on NO production was also evaluated.
Keywords: Monascus pilosus BCRC 38093; pyridine derivatives; NO production Monascus pilosus BCRC 38093; pyridine derivatives; NO production
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wu, M.-D.; Cheng, M.-J.; Yech, Y.-J.; Chen, Y.-L.; Chen, K.-P.; Chen, I.-S.; Yang, P.-H.; Yuan, G.-F. Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093. Molecules 2011, 16, 4719-4727.

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