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Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum
Institute of Liver Diseases, Shanghai Shuguang Hospital, Shanghai 201203, China
Shanghai Clinical Key Laboratory of Traditional Chinese Medicine, Shanghai Shuguang Hospital, Shanghai 201203, China
Key Laboratory of Liver and Kidney Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
E-Institute of Traditional Chinese Medicine Internal Medicine in Shanghai University, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330029, China
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
* Authors to whom correspondence should be addressed.
Received: 25 March 2011; in revised form: 13 May 2011 / Accepted: 18 May 2011 / Published: 26 May 2011
Abstract: A new unusual minor triterpenoid saponin, platycoside O (1), was isolated from the 75% EtOH extract obtained from the roots of Platycodon grandiflorum, together with four known saponins: platycoside M-3 (2), platycoside J (3), platycoside F (4) and platycoside B (5). The structure of 1 was determined as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-24-methoxyl, 24-oxo-28-oic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside on the basis of spectral analysis and chemical evidence.
Keywords: platycoside O; Platycodon grandiflorum; triterpenoid saponin
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Fu, W.-W.; Fu, J.-N.; Zhang, W.-M.; Sun, L.-X.; Pei, Y.-H.; Liu, P. Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum . Molecules 2011, 16, 4371-4378.
Fu W-W, Fu J-N, Zhang W-M, Sun L-X, Pei Y-H, Liu P. Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum . Molecules. 2011; 16(6):4371-4378.
Fu, Wen-Wei; Fu, Jin-Nan; Zhang, Wen-Meng; Sun, Li-Xin; Pei, Yue-Hu; Liu, Ping. 2011. "Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum ." Molecules 16, no. 6: 4371-4378.