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Molecules 2011, 16(6), 4371-4378; doi:10.3390/molecules16064371

Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum

1
Institute of Liver Diseases, Shanghai Shuguang Hospital, Shanghai 201203, China
2
Shanghai Clinical Key Laboratory of Traditional Chinese Medicine, Shanghai Shuguang Hospital, Shanghai 201203, China
3
Key Laboratory of Liver and Kidney Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
4
E-Institute of Traditional Chinese Medicine Internal Medicine in Shanghai University, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
5
Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330029, China
6
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
*
Authors to whom correspondence should be addressed.
Received: 25 March 2011 / Revised: 13 May 2011 / Accepted: 18 May 2011 / Published: 26 May 2011
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Abstract

A new unusual minor triterpenoid saponin, platycoside O (1), was isolated from the 75% EtOH extract obtained from the roots of Platycodon grandiflorum, together with four known saponins: platycoside M-3 (2), platycoside J (3), platycoside F (4) and platycoside B (5). The structure of 1 was determined as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-24-methoxyl, 24-oxo-28-oic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside on the basis of spectral analysis and chemical evidence.
Keywords: platycoside O; Platycodon grandiflorum; triterpenoid saponin platycoside O; Platycodon grandiflorum; triterpenoid saponin
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Fu, W.-W.; Fu, J.-N.; Zhang, W.-M.; Sun, L.-X.; Pei, Y.-H.; Liu, P. Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum . Molecules 2011, 16, 4371-4378.

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