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Molecules 2011, 16(6), 4371-4378; doi:10.3390/molecules16064371
Communication

Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum

1,2,3,4,* , 5, 6, 6, 6 and 3,4,*
1 Institute of Liver Diseases, Shanghai Shuguang Hospital, Shanghai 201203, China 2 Shanghai Clinical Key Laboratory of Traditional Chinese Medicine, Shanghai Shuguang Hospital, Shanghai 201203, China 3 Key Laboratory of Liver and Kidney Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China 4 E-Institute of Traditional Chinese Medicine Internal Medicine in Shanghai University, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China 5 Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330029, China 6 School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
* Authors to whom correspondence should be addressed.
Received: 25 March 2011 / Revised: 13 May 2011 / Accepted: 18 May 2011 / Published: 26 May 2011
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Abstract

A new unusual minor triterpenoid saponin, platycoside O (1), was isolated from the 75% EtOH extract obtained from the roots of Platycodon grandiflorum, together with four known saponins: platycoside M-3 (2), platycoside J (3), platycoside F (4) and platycoside B (5). The structure of 1 was determined as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-24-methoxyl, 24-oxo-28-oic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside on the basis of spectral analysis and chemical evidence.
Keywords: platycoside O; Platycodon grandiflorum; triterpenoid saponin platycoside O; Platycodon grandiflorum; triterpenoid saponin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fu, W.-W.; Fu, J.-N.; Zhang, W.-M.; Sun, L.-X.; Pei, Y.-H.; Liu, P. Platycoside O, a New Triterpenoid Saponin from the Roots of Platycodon grandiflorum . Molecules 2011, 16, 4371-4378.

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