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Molecules 2011, 16(5), 3580-3596; doi:10.3390/molecules16053580
Article

Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities

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1, 2,3, 1,4 and 1,2,3,4,*
Received: 16 March 2011 / Revised: 25 April 2011 / Accepted: 26 April 2011 / Published: 28 April 2011
(This article belongs to the Section Medicinal Chemistry)
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Abstract

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.
Keywords: phenylpropanoid glycosides; Rhodiola rosea L.; acetylcholinesterase/xanthine oxidase inhibitory activity phenylpropanoid glycosides; Rhodiola rosea L.; acetylcholinesterase/xanthine oxidase inhibitory activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Li, X.-D.; Kang, S.-T.; Li, G.-Y.; Li, X.; Wang, J.-H. Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities. Molecules 2011, 16, 3580-3596.

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