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Molecules 2011, 16(4), 3433-3443; doi:10.3390/molecules16043433
Article

Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants

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Received: 28 February 2011; in revised form: 2 April 2011 / Accepted: 8 April 2011 / Published: 21 April 2011
(This article belongs to the Section Metabolites)
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Abstract: Aqueous and ethanol extracts of different traditional Malaysian plants (Polygonum minus, Andrographis paniculata, Curcuma xanthorrhiza, Momordica charantia and Strobilanthes crispus) were evaluated for their antioxidant properties, total phenolic content and cytotoxic activity. Antioxidant activity was evaluated by using 1,1-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The results showed that ethanol extracts contain high antioxidant activities compared to aqueous extracts. The findings exhibited a strong correlation between antioxidant activity and the total phenol contents. In addition, all the plant extracts showed non-toxic effects against a normal human lung fibroblast cell line (Hs888Lu). Although traditionally aqueous extracts are used, we determined that ethanol extracts usually achieved better activity in the assays.
Keywords: antioxidant activity; total phenolic content; cytotoxicity; Malaysian plants antioxidant activity; total phenolic content; cytotoxicity; Malaysian plants
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Qader, S.W.; Abdulla, M.A.; Chua, L.S.; Najim, N.; Zain, M.M.; Hamdan, S. Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants. Molecules 2011, 16, 3433-3443.

AMA Style

Qader SW, Abdulla MA, Chua LS, Najim N, Zain MM, Hamdan S. Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants. Molecules. 2011; 16(4):3433-3443.

Chicago/Turabian Style

Qader, Suhailah Wasman; Abdulla, Mahmood Ameen; Chua, Lee Suan; Najim, Nigar; Zain, Mazatulikhma Mat; Hamdan, Salehhuddin. 2011. "Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants." Molecules 16, no. 4: 3433-3443.



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