Molecules 2011, 16(4), 3420-3432; doi:10.3390/molecules16043420
Article

Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents

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Received: 6 April 2011; in revised form: 19 April 2011 / Accepted: 20 April 2011 / Published: 21 April 2011
(This article belongs to the Special Issue Catalytic Asymmetric Synthesis)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Propylene carbonate is shown to be an environmentally friendly and sustainable replacement for dichloromethane and acetonitrile in proline-catalysed a-hydrazinations of aldehydes and ketones. Enantioselectivities comparable to those obtained in conventional solvents or ionic liquids can be obtained, even when using a lower catalyst loading.
Keywords: proline; amination; cyclic-carbonate
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MDPI and ACS Style

Beattie, C.; North, M.; Villuendas, P. Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents. Molecules 2011, 16, 3420-3432.

AMA Style

Beattie C, North M, Villuendas P. Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents. Molecules. 2011; 16(4):3420-3432.

Chicago/Turabian Style

Beattie, Christopher; North, Michael; Villuendas, Pedro. 2011. "Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents." Molecules 16, no. 4: 3420-3432.

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