Molecules 2011, 16(4), 3351-3359; doi:10.3390/molecules16043351
Article

Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate

1,†,* email, 1,†email, 2email, 3email, 1email, 1email, 1email and 1,* email
Received: 17 March 2011; in revised form: 1 April 2011 / Accepted: 2 April 2011 / Published: 19 April 2011
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Four new metabolites, including three new oblongolides named C1, P1, and X1 (1-3) and 6-hydroxyphomodiol (10), along with eight known compounds – oblongolides B (4), C (5), D (6), O (7), P (8) and U (9), (3R,4aR,5S,6R)-6-hydroxy-5-methylramulosin (11), and (3R)-5-methylmellein (12) – were isolated from the endophytic fungal strain Phomopsis sp. XZ-01 of Camptotheca acuminate. Their structures were elucidated by spectroscopic analyses, including 1H- and 13C-NMR, 2D NMR (HSQC, HMBC, 1H-1H COSY and NOESY) and HR-FT-MS. Cytotoxic activities of these compounds were evaluated. Some of them showed weak selective activities.
Keywords: Camptotheca acuminate; endophytic fungus; Phomopsis sp. XZ-01; oblongolides; new metabolites
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MDPI and ACS Style

Lin, T.; Wang, G.H.; Lin, X.; Hu, Z.Y.; Chen, Q.C.; Xu, Y.; Zhang, X.K.; Chen, H.F. Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate. Molecules 2011, 16, 3351-3359.

AMA Style

Lin T, Wang GH, Lin X, Hu ZY, Chen QC, Xu Y, Zhang XK, Chen HF. Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate. Molecules. 2011; 16(4):3351-3359.

Chicago/Turabian Style

Lin, Ting; Wang, Guang Hui; Lin, Xiang; Hu, Zhi Yu; Chen, Quan Cheng; Xu, Yang; Zhang, Xiao Kun; Chen, Hai Feng. 2011. "Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate." Molecules 16, no. 4: 3351-3359.

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