Molecules 2011, 16(4), 3351-3359; doi:10.3390/molecules16043351
Article

Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate

1 School of Pharmaceutical Sciences, Xiamen University, 422 South Siming Road, Xiamen, Fujian 361005, China 2 Institute of Life Sciences, Fuzhou University, No.2 Xueyuan Rd., University Town, Fuzhou, Fujian 350108, China 3 School of Life Sciences, Xiamen University, Fujian 361005, China These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 17 March 2011; in revised form: 1 April 2011 / Accepted: 2 April 2011 / Published: 19 April 2011
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Abstract: Four new metabolites, including three new oblongolides named C1, P1, and X1 (1-3) and 6-hydroxyphomodiol (10), along with eight known compounds – oblongolides B (4), C (5), D (6), O (7), P (8) and U (9), (3R,4aR,5S,6R)-6-hydroxy-5-methylramulosin (11), and (3R)-5-methylmellein (12) – were isolated from the endophytic fungal strain Phomopsis sp. XZ-01 of Camptotheca acuminate. Their structures were elucidated by spectroscopic analyses, including 1H- and 13C-NMR, 2D NMR (HSQC, HMBC, 1H-1H COSY and NOESY) and HR-FT-MS. Cytotoxic activities of these compounds were evaluated. Some of them showed weak selective activities.
Keywords: Camptotheca acuminate; endophytic fungus; Phomopsis sp. XZ-01; oblongolides; new metabolites

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MDPI and ACS Style

Lin, T.; Wang, G.H.; Lin, X.; Hu, Z.Y.; Chen, Q.C.; Xu, Y.; Zhang, X.K.; Chen, H.F. Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate. Molecules 2011, 16, 3351-3359.

AMA Style

Lin T, Wang GH, Lin X, Hu ZY, Chen QC, Xu Y, Zhang XK, Chen HF. Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate. Molecules. 2011; 16(4):3351-3359.

Chicago/Turabian Style

Lin, Ting; Wang, Guang Hui; Lin, Xiang; Hu, Zhi Yu; Chen, Quan Cheng; Xu, Yang; Zhang, Xiao Kun; Chen, Hai Feng. 2011. "Three New Oblongolides from Phomopsis sp. XZ-01, an Endophytic Fungus from Camptotheca acuminate." Molecules 16, no. 4: 3351-3359.

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