Molecules 2011, 16(4), 2833-2845; doi:10.3390/molecules16042833
Article

Synthesis and Herbicidal Activity of 5-(4-Hydroxybenzyl)-2-Thioxoimidazolidin-4-one Esters

Jintao Han 1 , Jinmin Wang 1 , Hongbo Dong 1 , Jianping Lei 1 , Mingan Wang 1,2,* email and Jianxin Fang 2
1 Department of Applied Chemistry, China Agricultural University, Beijing 100193, China 2 State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
* Author to whom correspondence should be addressed.
Received: 28 February 2011; in revised form: 16 March 2011 / Accepted: 25 March 2011 / Published: 30 March 2011
(This article belongs to the Special Issue Bioactive Compounds)
PDF Full-text Download PDF Full-Text [250 KB, uploaded 30 March 2011 12:57 CEST]
Abstract: A series of novel 5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one esters were synthesized under mild conditions by the reaction of 5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one and carboxylic acids with DCC and DMAP as the promoters. Their structures were confirmed by 1H-NMR, IR, ESI-MS and elemental analysis. The preliminary bioassy results indicated that some of compounds exhibit good herbicidal activity against Zea mays, Triticum aestivum and Arabidopsis thaliana. The further greenhouse test showed that compounds 6-16 and 6-28 have 60%, 50% and 50% efficacy against Stellaria media, Echinochloa crus-galli and Setaria viridis at 1,000 g/ha, respectively.
Keywords: 5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one esters; synthesis; herbicidal activity

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Han, J.; Wang, J.; Dong, H.; Lei, J.; Wang, M.; Fang, J. Synthesis and Herbicidal Activity of 5-(4-Hydroxybenzyl)-2-Thioxoimidazolidin-4-one Esters. Molecules 2011, 16, 2833-2845.

AMA Style

Han J, Wang J, Dong H, Lei J, Wang M, Fang J. Synthesis and Herbicidal Activity of 5-(4-Hydroxybenzyl)-2-Thioxoimidazolidin-4-one Esters. Molecules. 2011; 16(4):2833-2845.

Chicago/Turabian Style

Han, Jintao; Wang, Jinmin; Dong, Hongbo; Lei, Jianping; Wang, Mingan; Fang, Jianxin. 2011. "Synthesis and Herbicidal Activity of 5-(4-Hydroxybenzyl)-2-Thioxoimidazolidin-4-one Esters." Molecules 16, no. 4: 2833-2845.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert