Molecules 2011, 16(4), 2796-2801; doi:10.3390/molecules16042796
Article

Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila

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Received: 28 January 2011; in revised form: 21 March 2011 / Accepted: 23 March 2011 / Published: 30 March 2011
(This article belongs to the collection Bioactive Compounds)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 34 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 14 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher’s method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
Keywords: polyketide; chromone; indole alkaloid; Mosher; Exophiala pisciphila
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MDPI and ACS Style

Wang, C.-C.; Liu, H.-Z.; Liu, M.; Zhang, Y.-Y.; Li, T.-T.; Lin, X.-K. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila. Molecules 2011, 16, 2796-2801.

AMA Style

Wang C-C, Liu H-Z, Liu M, Zhang Y-Y, Li T-T, Lin X-K. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila. Molecules. 2011; 16(4):2796-2801.

Chicago/Turabian Style

Wang, Cui-Cui; Liu, Hai-Zhou; Liu, Ming; Zhang, Yu-Yan; Li, Tian-Tian; Lin, Xiu-Kun. 2011. "Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila." Molecules 16, no. 4: 2796-2801.

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