Molecules 2011, 16(4), 2796-2801; doi:10.3390/molecules16042796
Article

Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila

Cui-Cui Wang 1,2 email, Hai-Zhou Liu 1 email, Ming Liu 1 email, Yu-Yan Zhang 1 email, Tian-Tian Li 1,2  and Xiu-Kun Lin 1,* email
1 Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China 2 Graduate School of the Chinese Academy of Sciences, Beijing 100049, China
* Author to whom correspondence should be addressed.
Received: 28 January 2011; in revised form: 21 March 2011 / Accepted: 23 March 2011 / Published: 30 March 2011
(This article belongs to the Special Issue Bioactive Compounds)
PDF Full-text Download PDF Full-Text [217 KB, uploaded 30 March 2011 12:23 CEST]
Abstract: A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3–4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1–4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher’s method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.
Keywords: polyketide; chromone; indole alkaloid; Mosher; Exophiala pisciphila

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Wang, C.-C.; Liu, H.-Z.; Liu, M.; Zhang, Y.-Y.; Li, T.-T.; Lin, X.-K. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila. Molecules 2011, 16, 2796-2801.

AMA Style

Wang C-C, Liu H-Z, Liu M, Zhang Y-Y, Li T-T, Lin X-K. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila. Molecules. 2011; 16(4):2796-2801.

Chicago/Turabian Style

Wang, Cui-Cui; Liu, Hai-Zhou; Liu, Ming; Zhang, Yu-Yan; Li, Tian-Tian; Lin, Xiu-Kun. 2011. "Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila." Molecules 16, no. 4: 2796-2801.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert