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Molecules 2011, 16(4), 2785-2795; doi:10.3390/molecules16042785
Article

Antifeedant Triterpenoids from the Seeds and Bark of Lansium domesticum cv Kokossan (Meliaceae)

1, 1, 1,* , 2
,
2
 and
2
1 Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor 45363, Indonesia 2 Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
* Author to whom correspondence should be addressed.
Received: 31 December 2010 / Revised: 28 February 2011 / Accepted: 2 March 2011 / Published: 29 March 2011
(This article belongs to the collection Bioactive Compounds)
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Abstract

Two tetranortriterpenoids, kokosanolide A (1) and C (2) were isolated from the seeds and three onoceranoid-type triterpenoids: kokosanolide B (3), 8,14-secogammacera-7,14-diene-3,21-dione (4) and a 1.5:0.5 mixture of 8,14-secogammacera-7,14(27)-diene-3,21-dione (5) and compound 4 were isolated from the bark of kokossan (Lansium domesticum). Complete 1H- and 13C-NMR data of the triterpenoids 1-5 are reported. The triterpenoids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR, IR and HRMS spectral data. Triterpenoids 1-5 exhibited moderate to strong antifeedant activity against the fourth instar larvae of Epilachna vigintioctopunctata.
Keywords: kokosanolides; tetranortriterpenoid; onoceranoid; Lansium domesticum; meliaceae; antifeedant activity kokosanolides; tetranortriterpenoid; onoceranoid; Lansium domesticum; meliaceae; antifeedant activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Mayanti, T.; Tjokronegoro, R.; Supratman, U.; Mukhtar, M.R.; Awang, K.; Hadi, A.H.A. Antifeedant Triterpenoids from the Seeds and Bark of Lansium domesticum cv Kokossan (Meliaceae). Molecules 2011, 16, 2785-2795.

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