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Molecules 2011, 16(3), 2233-2252; doi:10.3390/molecules16032233
Review

Analgesic-like Activity of Essential Oils Constituents

Received: 4 January 2011; in revised form: 10 February 2011 / Accepted: 4 March 2011 / Published: 7 March 2011
(This article belongs to the Special Issue Neuroactive Compounds)
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Abstract: Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.
Keywords: analgesic; antinociceptive; essential oils; terpenes; natural products analgesic; antinociceptive; essential oils; terpenes; natural products
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

De Sousa, D.P. Analgesic-like Activity of Essential Oils Constituents. Molecules 2011, 16, 2233-2252.

AMA Style

De Sousa DP. Analgesic-like Activity of Essential Oils Constituents. Molecules. 2011; 16(3):2233-2252.

Chicago/Turabian Style

De Sousa, Damião Pergentino. 2011. "Analgesic-like Activity of Essential Oils Constituents." Molecules 16, no. 3: 2233-2252.



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