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Molecules 2011, 16(3), 2233-2252; doi:10.3390/molecules16032233
Review

Analgesic-like Activity of Essential Oils Constituents

Received: 4 January 2011 / Revised: 10 February 2011 / Accepted: 4 March 2011 / Published: 7 March 2011
(This article belongs to the Special Issue Neuroactive Compounds)
Download PDF [280 KB, 18 June 2014; original version 18 June 2014]

Abstract

Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.
Keywords: analgesic; antinociceptive; essential oils; terpenes; natural products analgesic; antinociceptive; essential oils; terpenes; natural products
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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De Sousa, D.P. Analgesic-like Activity of Essential Oils Constituents. Molecules 2011, 16, 2233-2252.

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