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Molecules 2011, 16(3), 2233-2252; doi:10.3390/molecules16032233
Review

Analgesic-like Activity of Essential Oils Constituents

Department of Physiology, Federal University of Sergipe, CEP 49100-000, São Cristóvão, SE, Brazil
Received: 4 January 2011 / Revised: 10 February 2011 / Accepted: 4 March 2011 / Published: 7 March 2011
(This article belongs to the Special Issue Neuroactive Compounds)
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Abstract

Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.
Keywords: analgesic; antinociceptive; essential oils; terpenes; natural products analgesic; antinociceptive; essential oils; terpenes; natural products
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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De Sousa, D.P. Analgesic-like Activity of Essential Oils Constituents. Molecules 2011, 16, 2233-2252.

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