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Molecules 2011, 16(2), 1579-1592; doi:10.3390/molecules16021579
Article

In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum

1,†, 2, 1,†,* , 3, 3 and 4
1 Department of Landscape Plants, Chengdu Campus of Sichuan Agriculture University, Chengdu 611130, China 2 United States Geological Survey, Lake Michigan Ecological Research Station, Porter, IN 46304, USA 3 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China 4 College of Life Sciences, Sichuan University, Chengdu 610064, China These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 12 January 2011 / Revised: 9 February 2011 / Accepted: 11 February 2011 / Published: 14 February 2011
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Abstract

The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about  484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant.
Keywords: Dendrobium denneanum; polysaccharide; antioxidant activity Dendrobium denneanum; polysaccharide; antioxidant activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Luo, A.; Ge, Z.; Fan, Y.; Luo, A.; Chun, Z.; He, X. In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum. Molecules 2011, 16, 1579-1592.

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