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In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
Department of Landscape Plants, Chengdu Campus of Sichuan Agriculture University, Chengdu 611130, China
United States Geological Survey, Lake Michigan Ecological Research Station, Porter, IN 46304, USA
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
College of Life Sciences, Sichuan University, Chengdu 610064, China
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 12 January 2011; in revised form: 9 February 2011 / Accepted: 11 February 2011 / Published: 14 February 2011
Abstract: The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about 484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant.
Keywords: Dendrobium denneanum; polysaccharide; antioxidant activity
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Luo, A.; Ge, Z.; Fan, Y.; Luo, A.; Chun, Z.; He, X. In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum. Molecules 2011, 16, 1579-1592.
Luo A, Ge Z, Fan Y, Luo A, Chun Z, He X. In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum. Molecules. 2011; 16(2):1579-1592.
Luo, Aoxue; Ge, Zhongfu; Fan, Yijun; Luo, Aoshuang; Chun, Ze; He, XingJin. 2011. "In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum." Molecules 16, no. 2: 1579-1592.