Molecules 2011, 16(12), 9783-9791; doi:10.3390/molecules16129783
Article

Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels

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Received: 14 November 2011; in revised form: 22 November 2011 / Accepted: 22 November 2011 / Published: 25 November 2011
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Quercetin and quercetin glycosides are physiologically active flavonol molecules that have been attributed numerous health benefits. Recovery of such molecules from plant matrices depends on a variety of factors including polarity of the extraction solvent. Among the solvents of a wide range of dielectric constants, methanol recovered the most quercetin and its glycosides from dehydrated ‘Idared’ apple peels. When ultra-sonication was employed to facilitate the extraction, exposure of 15 min of ultrasound wavelengths of dehydrated apple peel powder in 80% to 100% (v/v) methanol in 1:50 (w:v) solid to solvent ratio provided the optimum extraction conditions for quercetin and its glycosides. Acidification of extraction solvent with 0.1% (v/v) or higher concentrations of HCl led to hydrolysis of naturally occurring quercetin glycosides into the aglycone as an extraction artifact.
Keywords: flavonols; extraction; ultrasonication; quercetin; quercetin glycoside; acidification; apple
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MDPI and ACS Style

Vasantha Rupasinghe, H.P.; Kathirvel, P.; Huber, G.M. Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels. Molecules 2011, 16, 9783-9791.

AMA Style

Vasantha Rupasinghe HP, Kathirvel P, Huber GM. Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels. Molecules. 2011; 16(12):9783-9791.

Chicago/Turabian Style

Vasantha Rupasinghe, H. P.; Kathirvel, Priya; Huber, Gwendolyn M. 2011. "Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels." Molecules 16, no. 12: 9783-9791.

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