Molecules 2011, 16(11), 8973-8980; doi:10.3390/molecules16118973
Article

Two New Xanthones from Calophyllum nodusum (Guttiferae)

1 Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia 2 Department of Biology, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia
* Author to whom correspondence should be addressed.
Received: 23 September 2011; Accepted: 17 October 2011 / Published: 25 October 2011
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Abstract: The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone (1a) and trapezifolixanthone A (2). Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data.
Keywords: Calophyllum nodusum; nodusuxanthone; trapezifolixanthone A; lupeol; stigmasterol

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MDPI and ACS Style

Nasir, N.M.; Rahmani, M.; Shaari, K.; Ee, G.C.L.; Go, R.; Kassim, N.K.; Muhamad, S.N.K.; Iskandar, M.J. Two New Xanthones from Calophyllum nodusum (Guttiferae). Molecules 2011, 16, 8973-8980.

AMA Style

Nasir NM, Rahmani M, Shaari K, Ee GCL, Go R, Kassim NK, Muhamad SNK, Iskandar MJ. Two New Xanthones from Calophyllum nodusum (Guttiferae). Molecules. 2011; 16(11):8973-8980.

Chicago/Turabian Style

Nasir, Nadiah Mad; Rahmani, Mawardi; Shaari, Khozirah; Ee, Gwendoline Cheng Lian; Go, Rusea; Kassim, Nur Kartinee; Muhamad, Siti Noor Kamilah; Iskandar, Mohd Johadi. 2011. "Two New Xanthones from Calophyllum nodusum (Guttiferae)." Molecules 16, no. 11: 8973-8980.

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