Next Article in Journal
Optimization of an Efficient Semi-Solid Culture Protocol for Sterilization and Plant Regeneration of Centella asiatica (L.) as a Medicinal Herb
Previous Article in Journal
Direct One-Pot Synthesis of Primary 4-Amino-2,3-diaryl-quinolines via Suzuki-Miyaura Cross-Coupling of 2-Aryl-4-azido-3-iodoquinolines with Arylboronic Acids
Molecules 2011, 16(11), 8973-8980; doi:10.3390/molecules16118973
Article

Two New Xanthones from Calophyllum nodusum (Guttiferae)

1, 1,* , 1, 1, 2, 1, 1 and 1
1 Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia 2 Department of Biology, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia
* Author to whom correspondence should be addressed.
Received: 23 September 2011 / Accepted: 17 October 2011 / Published: 25 October 2011
Download PDF [192 KB, uploaded 18 June 2014]

Abstract

The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone (1a) and trapezifolixanthone A (2). Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data.
Keywords: Calophyllum nodusum; nodusuxanthone; trapezifolixanthone A; lupeol; stigmasterol Calophyllum nodusum; nodusuxanthone; trapezifolixanthone A; lupeol; stigmasterol
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Nasir, N.M.; Rahmani, M.; Shaari, K.; Ee, G.C.L.; Go, R.; Kassim, N.K.; Muhamad, S.N.K.; Iskandar, M.J. Two New Xanthones from Calophyllum nodusum (Guttiferae). Molecules 2011, 16, 8973-8980.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert