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Molecules 2011, 16(1), 888-899; doi:10.3390/molecules16010888
Article

Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006

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Received: 22 November 2010; in revised form: 31 December 2010 / Accepted: 18 January 2011 / Published: 21 January 2011
(This article belongs to the Special Issue Toxins - Organic and Analytical Chemistry)
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Abstract: Dinophysis spp. blooms and related shellfish toxicity events of diarrhetic shellfish poisoning (DSP) have been the most reported toxicity event through the Croatian National monitoring program. With the aim to characterize the DSP toxin profile in shellfish farmed in Croatia, for the first time a complete analysis of the toxin profile of Croatian mussels has been carried out using the LC-MS/MS technique. The obtained results showed okadaic acid (OA) as the main toxin contaminating Croatian mussels at that time. The maximum concentration of OA in shellfish tissue was recorded 12 days after the Dinophysis fortii bloom, thus suggesting that rapid growth of the toxin level in the shellfish occurred in the first week after the bloom while it was slower in the second week. Furthermore, the presence of only OA at concentrations which could endanger human health suggests D. fortii as the main organism responsible for the toxic event that occurred in Lim Bay. The presence of gymnodimine and spirolides in Croatian mussel has been detected for the first time, while the presence of yessotoxin and pectenotoxin-2 is confirmed.
Keywords: diarrhetic shellfish poisoning; okadaic acid; Dinophysis fortii; Adriatic sea diarrhetic shellfish poisoning; okadaic acid; Dinophysis fortii; Adriatic sea
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Nincevic Gladan, Z.; Ujevic, I.; Milandri, A.; Marasovic, I.; Ceredi, A.; Pigozzi, S.; Arapov, J.; Skejic, S. Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006. Molecules 2011, 16, 888-899.

AMA Style

Nincevic Gladan Z, Ujevic I, Milandri A, Marasovic I, Ceredi A, Pigozzi S, Arapov J, Skejic S. Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006. Molecules. 2011; 16(1):888-899.

Chicago/Turabian Style

Nincevic Gladan, Zivana; Ujevic, Ivana; Milandri, Anna; Marasovic, Ivona; Ceredi, Alfiero; Pigozzi, Silvia; Arapov, Jasna; Skejic, Sanda. 2011. "Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006." Molecules 16, no. 1: 888-899.


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