Molecules 2011, 16(1), 466-476; doi:10.3390/molecules16010466

Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana

1, 2,* email, 3, 2, 3, 3, 3,* email and 1
Received: 17 November 2010; in revised form: 5 January 2011 / Accepted: 7 January 2011 / Published: 10 January 2011
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The screening of several Chinese medicinal herbs for insecticidal principles showed that Euphorbia fischeriana roots possessed significant feeding deterrent activity against two stored-product insects (Tribolium castaneum and Sitophilus zeamais). From ethanol extract, four feeding deterrents were isolated by bioassay-guided fractionation. The compounds were identified as jolkinolide B, 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate, 17-hydroxyjolkinolide A and B on the basis of their phytochemical and spectral data. Jolkinolide B and 17-hydroxyjolkinolide B possessed strong feeding deterrent activities against S. zeamais (EC50 = 342.1 and 543.9 ppm, respectively) and T. castaneum adults (EC50 = 361.4 and 551.5 ppm, respectively). 17-Hydroxyjolkinolide A and 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate A also exhibited feeding deterrent activity against the two grain storage insects with EC50 values of 631.9 and 884.3 ppm for S. zeamais and 656.5 and 1058.4 ppm for T. castaneum adults.
Keywords: feeding deterrents; Euphorbia fischeriana; Tribolium castaneum; Sitophilus zeamais
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MDPI and ACS Style

Geng, Z.F.; Liu, Z.L.; Wang, C.F.; Liu, Q.Z.; Shen, S.M.; Liu, Z.M.; Du, S.S.; Deng, Z.W. Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana. Molecules 2011, 16, 466-476.

AMA Style

Geng ZF, Liu ZL, Wang CF, Liu QZ, Shen SM, Liu ZM, Du SS, Deng ZW. Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana. Molecules. 2011; 16(1):466-476.

Chicago/Turabian Style

Geng, Zhu Feng; Liu, Zhi Long; Wang, Cheng Fang; Liu, Qi Zhi; Shen, Sheng Min; Liu, Zi Mu; Du, Shu Shan; Deng, Zhi Wei. 2011. "Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana." Molecules 16, no. 1: 466-476.

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