Abstract: The screening of several Chinese medicinal herbs for insecticidal principles showed that Euphorbia fischeriana roots possessed significant feeding deterrent activity against two stored-product insects (Tribolium castaneum and Sitophilus zeamais). From ethanol extract, four feeding deterrents were isolated by bioassay-guided fractionation. The compounds were identified as jolkinolide B, 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate, 17-hydroxyjolkinolide A and B on the basis of their phytochemical and spectral data. Jolkinolide B and 17-hydroxyjolkinolide B possessed strong feeding deterrent activities against S. zeamais (EC50 = 342.1 and 543.9 ppm, respectively) and T. castaneum adults (EC50 = 361.4 and 551.5 ppm, respectively). 17-Hydroxyjolkinolide A and 12-deoxyphorbol 13-(9Z)-octadecenoate 20-acetate A also exhibited feeding deterrent activity against the two grain storage insects with EC50 values of 631.9 and 884.3 ppm for S. zeamais and 656.5 and 1058.4 ppm for T. castaneum adults.
Keywords: feeding deterrents; Euphorbia fischeriana; Tribolium castaneum; Sitophilus zeamais
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Geng, Z.F.; Liu, Z.L.; Wang, C.F.; Liu, Q.Z.; Shen, S.M.; Liu, Z.M.; Du, S.S.; Deng, Z.W. Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana. Molecules 2011, 16, 466-476.
Geng ZF, Liu ZL, Wang CF, Liu QZ, Shen SM, Liu ZM, Du SS, Deng ZW. Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana. Molecules. 2011; 16(1):466-476.
Geng, Zhu Feng; Liu, Zhi Long; Wang, Cheng Fang; Liu, Qi Zhi; Shen, Sheng Min; Liu, Zi Mu; Du, Shu Shan; Deng, Zhi Wei. 2011. "Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana." Molecules 16, no. 1: 466-476.