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Isolation and Crystal Structure of Marcanine A from Polyalthia plagioneura
Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Hainan 571158, China
College of chemistry and chemical engineering, Hainan Normal University, Hainan 571158, China
* Author to whom correspondence should be addressed.
Received: 7 July 2010; in revised form: 18 August 2010 / Accepted: 27 August 2010 / Published: 9 September 2010
Abstract: Marcanine A was isolated from the stems of Polyalthia plagioneura as light yellow crystals. The molecular and crystal structures have been determined by 1D,2D-NMR and X-ray diffraction analysis. It crystallizes in the triclinic system, space group P-1 with a = 5.2140(5)Å, b = 10.1871(11)Å, c = 11.0709(13)Å, α = 110.452(2)º, β = 103.376(2)°, γ = 90.1870(10)°, V = 533.74(10)Å3, Z = 2. There are three intermolecular hydrogen bonds in a unit cell. It displays some inhibitory activities towards four kinds of human tumor cells, including BEL-7402, K562, SPCA-1and SGC-7409.
Keywords: Polyalthia plagioneura; marcanine A; NMR; X-ray diffraction; anticancer activities
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MDPI and ACS Style
Liu, B.; Wang, L.; Chen, G.; Han, C.; Wang, J. Isolation and Crystal Structure of Marcanine A from Polyalthia plagioneura. Molecules 2010, 15, 6349-6356.
Liu B, Wang L, Chen G, Han C, Wang J. Isolation and Crystal Structure of Marcanine A from Polyalthia plagioneura. Molecules. 2010; 15(9):6349-6356.
Liu, Bingjing; Wang, Lin; Chen, Guangying; Han, Changri; Wang, Jing. 2010. "Isolation and Crystal Structure of Marcanine A from Polyalthia plagioneura." Molecules 15, no. 9: 6349-6356.