Molecules 2010, 15(8), 5782-5796; doi:10.3390/molecules15085782
Article

Asymmetric Synthesis of α-Aminophosphonates Using the Inexpensive Chiral Catalyst 1,1’-Binaphthol Phosphate

email, email, * email, email, email, email and email
Received: 19 June 2010; in revised form: 18 August 2010 / Accepted: 20 August 2010 / Published: 24 August 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Asymmetric addition under mild conditions of dialkyl phosphites on aldimines derived from cinnamaldehyde catalyzed by the inexpensive chiral organocatalyst (R)-3,3’-[4-fluorophenyl]2-1,1’-binaphthol phosphate has been found effective to give new α-amino-phosphonates 9 in moderate yields (30–65%) and enantiomeric excess (8.4%–61.9%).
Keywords: α-aminophosphonate derivatives; aldimines; cinnamaldehyde; chiral organo- catalyst; asymmetric addition
PDF Full-text Download PDF Full-Text [267 KB, uploaded 18 June 2014 19:34 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Xu, W.; Zhang, S.; Yang, S.; Jin, L.-H.; Bhadury, P.S.; Hu, D.-Y.; Zhang, Y. Asymmetric Synthesis of α-Aminophosphonates Using the Inexpensive Chiral Catalyst 1,1’-Binaphthol Phosphate. Molecules 2010, 15, 5782-5796.

AMA Style

Xu W, Zhang S, Yang S, Jin L-H, Bhadury PS, Hu D-Y, Zhang Y. Asymmetric Synthesis of α-Aminophosphonates Using the Inexpensive Chiral Catalyst 1,1’-Binaphthol Phosphate. Molecules. 2010; 15(8):5782-5796.

Chicago/Turabian Style

Xu, Weiming; Zhang, Sha; Yang, Song; Jin, Lin-Hong; Bhadury, Pinaki S.; Hu, De-Yu; Zhang, Yuping. 2010. "Asymmetric Synthesis of α-Aminophosphonates Using the Inexpensive Chiral Catalyst 1,1’-Binaphthol Phosphate." Molecules 15, no. 8: 5782-5796.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert