Next Article in Journal
Pharmaceutical Composition of Valsartan: β-Cyclodextrin: Physico–Chemical Characterization and Anti-Hypertensive Evaluation
Previous Article in Journal
Receptor-Based Virtual Screening of EGFR Kinase Inhibitors from the NCI Diversity Database
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2010, 15(6), 4055-4066; doi:10.3390/molecules15064055

Determination of the Volatile Constituents in Radix Flemingiae Philippinensis by GC-MS and a Heuristic Evolving Latent Projection Method

1
Department of Chemistry and Pharmaceutical, Quzhou College, Quzhou 324000, China
2
Quzhou Center of Calibration and Testing for Quality and Technical Supervision, Quzhou 324000, China
3
Changde Institute for Drug Control, Changde 415000, China
*
Author to whom correspondence should be addressed.
Received: 10 March 2010 / Revised: 24 May 2010 / Accepted: 28 May 2010 / Published: 4 June 2010
Download PDF [253 KB, uploaded 18 June 2014]

Abstract

With the help of chemometric resolution methods, a technique for qualitative and quantitative determination of the volatile chemical constituents in Radix Flemingiae Philippinensis by chromatography-mass spectrometry was developed. After the overlapping chromatographic peaks were resolved into pure chromatograms and spectra using a heuristic evolving latent projections (HELP) method, qualitative analysis was performed by similarity search of the obtained pure mass spectrum of each component in the NIST library and the quantitative results were obtained by calculating the total two-way response volume. A total of 63 components were separated and 55 components were identified, accounting for 90.62% of the total content. The main components were farnesol isomer and β-caryophyllene, accounting for 31.33% and 12.60% of the total content, respectively. The obtained results can provide useful information for further study and development of Radix Flemingiae Philippinensis.
Keywords: chemometrics; heuristic evolving latent projections (HELP); gas chromatography-mass spectrometry (GC-MS); Radix Flemingiae Philippinensis; the volatile constituents chemometrics; heuristic evolving latent projections (HELP); gas chromatography-mass spectrometry (GC-MS); Radix Flemingiae Philippinensis; the volatile constituents
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Xie, J.-W.; Hu, W.; Zhou, Z.-L.; Huang, L.-F.; Wang, Y.-L.; Fang, J.-J.; He, Y.-B. Determination of the Volatile Constituents in Radix Flemingiae Philippinensis by GC-MS and a Heuristic Evolving Latent Projection Method. Molecules 2010, 15, 4055-4066.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top