Molecules 2010, 15(5), 3634-3642; doi:10.3390/molecules15053634
Article

Synthesis and Effect on Human HepG2 Cells of 1,2-bis- (2-Methylallyl)disulfane

1,* email, 1email, 1 and 2
Received: 16 April 2010; in revised form: 11 May 2010 / Accepted: 12 May 2010 / Published: 18 May 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: 1,2-bis(2-methylallyl)disulfane was synthesized from sodium sulfide and 3-chloro-2-methylpropylene. The structure of the target product was confirmed by GC-MS, 1H-NMR and elemental analysis. Cell viability assay, flow-cytometric analysis and protein expression results showed that 1,2-bis(2-methylallyl)disulfane could significantly inhibit the proliferation, and induce the apoptosis of human HepG2 cells.
Keywords: 1,2-bis(2-methylallyl)disulfane; identification; apoptosis
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MDPI and ACS Style

Ji, C.; Ren, F.; Dai, J.; Xu, M. Synthesis and Effect on Human HepG2 Cells of 1,2-bis- (2-Methylallyl)disulfane. Molecules 2010, 15, 3634-3642.

AMA Style

Ji C, Ren F, Dai J, Xu M. Synthesis and Effect on Human HepG2 Cells of 1,2-bis- (2-Methylallyl)disulfane. Molecules. 2010; 15(5):3634-3642.

Chicago/Turabian Style

Ji, Chunxiao; Ren, Fenglian; Dai, Jun; Xu, Ming. 2010. "Synthesis and Effect on Human HepG2 Cells of 1,2-bis- (2-Methylallyl)disulfane." Molecules 15, no. 5: 3634-3642.

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