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Molecules 2010, 15(5), 3593-3601; doi:10.3390/molecules15053593
Article

Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

1, 1, 1, 2,* , 1,2, 1,2,3 and 1,2,*
1 School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China 2 State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China 3 Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China
* Authors to whom correspondence should be addressed.
Received: 23 April 2010 / Revised: 10 May 2010 / Accepted: 13 May 2010 / Published: 17 May 2010
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Abstract

An efficient one-pot method to generate structurally diverse and medicinally interesting pyrazolone derivatives in good to excellent yields of 51–98% under microwave irradiation and solvent-free conditions has been developed.
Keywords: microwave-assisted reactions; one-pot; pyrazolones microwave-assisted reactions; one-pot; pyrazolones
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Ma, R.; Zhu, J.; Liu, J.; Chen, L.; Shen, X.; Jiang, H.; Li, J. Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions. Molecules 2010, 15, 3593-3601.

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