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Molecules 2010, 15(5), 2949-2961; doi:10.3390/molecules15052949
Article

Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines

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,
 and *
Laboratoire de Pharmacochimie Radicalaire, Faculté de Pharmacie, Universités d’Aix-Marseille I, II et III - UMR CNRS 6264 , Laboratoire Chimie Provence, 27 Boulevard Jean Moulin, 13385 Marseille cedex 05, France
* Author to whom correspondence should be addressed.
Received: 24 March 2010 / Revised: 8 April 2010 / Accepted: 21 April 2010 / Published: 27 April 2010
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Abstract

New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions.
Keywords: quinazoline; Suzuki-Miyaura reaction; microwaves; SRN1 quinazoline; Suzuki-Miyaura reaction; microwaves; SRN1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Kabri, Y.; Verhaeghe, P.; Gellis, A.; Vanelle, P. Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines. Molecules 2010, 15, 2949-2961.

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