Next Article in Journal
Cationic Heteroleptic Cyclometalated IridiumIII Complexes Containing Phenyl-Triazole and Triazole-Pyridine Clicked Ligands
Previous Article in Journal
Antioxidant Capacities and Phenolic Levels of Different Varieties of Serbian White Wines
Article Menu

Article Versions

Export Article

Open AccessArticle
Molecules 2010, 15(3), 2028-2038; doi:10.3390/molecules15032028

Acetamide Derivatives with Antioxidant Activity and Potential Anti-Inflammatory Activity

1
Department of Pharmaceutical Sciences, University of Salerno, Fisciano (SA), Italy
2
Institute of Biomolecular Chemistry, CNR, Pozzuoli (NA), Italy
3
Department of Pharmaceutical Sciences, University of Cosenza, Arcavacate di Rende (CS), Italy
*
Author to whom correspondence should be addressed.
Received: 2 February 2010 / Revised: 9 March 2010 / Accepted: 18 March 2010 / Published: 23 March 2010
Download PDF [235 KB, uploaded 18 June 2014]

Abstract

This study reports the synthesis and antioxidant activity of some new acetamide derivatives. The compounds’ structures were elucidated by NMR analysis and their melting points were measured. The in vitro antioxidant activity of these compounds was tested by evaluating the amount of scavenged ABTS radical and estimating ROS and NO production in tBOH- or LPS-stimulated J774.A1 macrophages. All compounds were tested for their effect on cell viability by an MTT assay and by a Brine Shrimp Test.
Keywords: amides; antioxidant; antiproliferative activity; brine shrimp test amides; antioxidant; antiproliferative activity; brine shrimp test
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Autore, G.; Caruso, A.; Marzocco, S.; Nicolaus, B.; Palladino, C.; Pinto, A.; Popolo, A.; Sinicropi, M.S.; Tommonaro, G.; Saturnino, C. Acetamide Derivatives with Antioxidant Activity and Potential Anti-Inflammatory Activity. Molecules 2010, 15, 2028-2038.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top