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Molecules 2010, 15(3), 1097-1102; doi:10.3390/molecules15031097
Article

Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook

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 and *
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
* Author to whom correspondence should be addressed.
Received: 2 December 2009 / Revised: 18 January 2010 / Accepted: 19 January 2010 / Published: 26 February 2010
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Abstract

A new flavone, named crotoncaudatin (1), was isolated from the stems of Croton caudatus Geisel. var. tomentosus Hook., together with nine known analogues: 3,5,6,7,8,3′,4′-heptamethoxyflavone (2), tangeretin (3), nobiletin (4), 5,6,7,4′-tetramethoxy-flavone (5), sinensetin (6), kaempferol (7), tiliroside (8), kaempferol-3-O-rutinoside (9) and rutin (10). The structures of the above compounds were established by a combination of spectroscopic methods, including HR-ESI-MS, 1H-NMR, 13C-NMR, HMQC and HMBC spectra. All compounds were isolated from and identified in this species for the first time and compounds 1-6 are new for the genus Croton.
Keywords: Croton caudatus Geisel.var. tomentosus Hook; Euphorbiaceae; flavonoids; crotoncaudatin Croton caudatus Geisel.var. tomentosus Hook; Euphorbiaceae; flavonoids; crotoncaudatin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Zou, G.-A.; Su, Z.-H.; Zhang, H.-W.; Wang, Y.; Yang, J.-S.; Zou, Z.-M. Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook. Molecules 2010, 15, 1097-1102.

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