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Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
* Author to whom correspondence should be addressed.
Received: 2 December 2009; in revised form: 18 January 2010 / Accepted: 19 January 2010 / Published: 26 February 2010
Abstract: A new flavone, named crotoncaudatin (1), was isolated from the stems of Croton caudatus Geisel. var. tomentosus Hook., together with nine known analogues: 3,5,6,7,8,3′,4′-heptamethoxyflavone (2), tangeretin (3), nobiletin (4), 5,6,7,4′-tetramethoxy-flavone (5), sinensetin (6), kaempferol (7), tiliroside (8), kaempferol-3-O-rutinoside (9) and rutin (10). The structures of the above compounds were established by a combination of spectroscopic methods, including HR-ESI-MS, 1H-NMR, 13C-NMR, HMQC and HMBC spectra. All compounds were isolated from and identified in this species for the first time and compounds 1-6 are new for the genus Croton.
Keywords: Croton caudatus Geisel.var. tomentosus Hook; Euphorbiaceae; flavonoids; crotoncaudatin
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Zou, G.-A.; Su, Z.-H.; Zhang, H.-W.; Wang, Y.; Yang, J.-S.; Zou, Z.-M. Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook. Molecules 2010, 15, 1097-1102.
Zou G-A, Su Z-H, Zhang H-W, Wang Y, Yang J-S, Zou Z-M. Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook. Molecules. 2010; 15(3):1097-1102.
Zou, Guo-An; Su, Zhi-Heng; Zhang, Hong-Wu; Wang, Yuan; Yang, Jun-Shan; Zou, Zhong-Mei. 2010. "Flavonoids from the Stems of Croton caudatus Geisel. var. tomentosus Hook." Molecules 15, no. 3: 1097-1102.