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Molecules 2010, 15(2), 1074-1081; doi:10.3390/molecules15021074

Synthesis and Biological activity of 4-(4,6-Disubstituted-pyrimidin-2-yloxy)phenoxy Acetates

1
College of Chemistry and Material Science, Shandong Agricultural University, Taian 271018, China
2
College of Plant Protection, Shandong Agricultural University, Taian 271018, China
*
Author to whom correspondence should be addressed.
Received: 14 January 2010 / Revised: 1 February 2010 / Accepted: 20 February 2010 / Published: 23 February 2010
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Abstract

Ten novel 4-(4,6-dimethoxypyrimidin-2-yloxy)phenoxy acetates and 4-(4,6-dimethylpyrimidin-2-yloxy)phenoxy acetates were synthesized with hydroquinone, 2-methylsulfonyl-4,6-disubstituted-pyrimidine and chloroacetic ester as starting materials. The products were characterized by IR, 1H-NMR, MS spectra and elemental analyses. Preliminary bioassay indicates that the target compounds possess high herbicidal activity against monocotyledonous plants such as Digitaria sanguinalis L. at concentrations of 100 mg/L and 50 mg/L.
Keywords: pyrimidine; phenoxyacetate; synthesis; herbicidal activity pyrimidine; phenoxyacetate; synthesis; herbicidal activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Jiang, L.; Wang, H.; Wang, M.; Teng, X. Synthesis and Biological activity of 4-(4,6-Disubstituted-pyrimidin-2-yloxy)phenoxy Acetates. Molecules 2010, 15, 1074-1081.

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