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Application of Cycloaddition Reactions to the Syntheses of Novel Boron Compounds
Institute of Chemical and Engineering Sciences, No. 1 Pesek Road, Jurong Island 627833, Singapore
Department of Chemistry, Southern Methodist University, Dallas, Texas 75275, USA
Department of Chemistry and Chemical Biology, Northern Illinois University, DeKalb, Illinois 60115, USA
* Authors to whom correspondence should be addressed.
Received: 11 October 2010; in revised form: 16 December 2010 / Accepted: 20 December 2010 / Published: 21 December 2010
Abstract: This review covers the application of cycloaddition reactions in forming the boron-containing compounds such as symmetric star-shaped boron-enriched dendritic molecules, nano-structured boron materials and aromatic boronic esters. The resulting boron compounds are potentially important reagents for both materials science and medical applications such as in boron neutron capture therapy (BNCT) in cancer treatment and as drug delivery agents and synthetic intermediates for carbon-carbon cross-coupling reactions. In addition, the use of boron cage compounds in a number of cycloaddition reactions to synthesize unique aromatic species will be reviewed briefly.
Keywords: cycloaddition reaction; carborane; boron neutron capture therapy; boron-based material; boron compounds; cross-coupling reaction; boron reagent
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Zhu, Y.; Siwei, X.; Maguire, J.A.; Hosmane, N.S. Application of Cycloaddition Reactions to the Syntheses of Novel Boron Compounds. Molecules 2010, 15, 9437-9449.
Zhu Y, Siwei X, Maguire JA, Hosmane NS. Application of Cycloaddition Reactions to the Syntheses of Novel Boron Compounds. Molecules. 2010; 15(12):9437-9449.
Zhu, Yinghuai; Siwei, Xiao; Maguire, John A.; Hosmane, Narayan S. 2010. "Application of Cycloaddition Reactions to the Syntheses of Novel Boron Compounds." Molecules 15, no. 12: 9437-9449.