A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments

doi:10.3390/molecules15129298

This article is

freely available
re-usable

Molecules 2010, 15(12), 9298-9307; doi:10.3390/molecules15129298

Article

A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments

Xiao-Ling Li^1,3,†, Min-Juan Xu^2,†, Yi-Lei Zhao¹ and Jun Xu^1,*

¹ Key Laboratory of MOE for Microbial metabolism and School of Life Science & Biotechnology, State Key Laboratory of Ocean Engineering, Shanghai JiaoTong University, Shanghai 200240, China ² Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China ³ Key Laboratory of Marine Biogenetic Resources, the Third Institute of Oceanography SOA, Xiamen, Fujian 361005, China ^† These authors contributed equally to this work.

* Author to whom correspondence should be addressed.

Received: 24 October 2010; in revised form: 30 November 2010 / Accepted: 7 December 2010 / Published: 15 December 2010

(This article belongs to the Section Natural Products)

Download PDF Full-Text [244 KB, uploaded 15 December 2010 16:16 CET]

Abstract: Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N-butanoic acid-3¢-(9¢-methyl-8¢-propen-7¢-one)-amide]-benzo[f][1,7]naphthyridine-2-one (1) was isolated from Streptomyces albogriseolus originating from mangrove sediments. The structure of compound 1 was elucidated by extensive spectroscopic data analyses and verified by the ¹³C-NMR calculation at the B3LYP/6-311+G(2d,p) level of theory.

Keywords: Streptomyces albogriseolus; mangrove; benzo[f][1,7]naphthyridine

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Li, X.-L.; Xu, M.-J.; Zhao, Y.-L.; Xu, J. A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments. Molecules 2010, 15, 9298-9307.

AMA Style

Li X-L, Xu M-J, Zhao Y-L, Xu J. A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments. Molecules. 2010; 15(12):9298-9307.

Chicago/Turabian Style

Li, Xiao-Ling; Xu, Min-Juan; Zhao, Yi-Lei; Xu, Jun. 2010. "A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments." Molecules 15, no. 12: 9298-9307.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert