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A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments
Key Laboratory of MOE for Microbial metabolism and School of Life Science & Biotechnology, State Key Laboratory of Ocean Engineering, Shanghai JiaoTong University, Shanghai 200240, China
Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China
Key Laboratory of Marine Biogenetic Resources, the Third Institute of Oceanography SOA, Xiamen, Fujian 361005, China
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 24 October 2010; in revised form: 30 November 2010 / Accepted: 7 December 2010 / Published: 15 December 2010
Abstract: Mangrove Streptomyces represent a rich source of novel bioactive compounds in medicinal research. A novel alkaloid, named 1-N-methyl-3-methylamino-[N-butanoic acid-3¢-(9¢-methyl-8¢-propen-7¢-one)-amide]-benzo[f][1,7]naphthyridine-2-one (1) was isolated from Streptomyces albogriseolus originating from mangrove sediments. The structure of compound 1 was elucidated by extensive spectroscopic data analyses and verified by the 13C-NMR calculation at the B3LYP/6-311+G(2d,p) level of theory.
Keywords: Streptomyces albogriseolus; mangrove; benzo[f][1,7]naphthyridine
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MDPI and ACS Style
Li, X.-L.; Xu, M.-J.; Zhao, Y.-L.; Xu, J. A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments. Molecules 2010, 15, 9298-9307.
Li X-L, Xu M-J, Zhao Y-L, Xu J. A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments. Molecules. 2010; 15(12):9298-9307.
Li, Xiao-Ling; Xu, Min-Juan; Zhao, Yi-Lei; Xu, Jun. 2010. "A Novel Benzo[f][1,7]Naphthyridine Produced by Streptomyces Albogriseolus from Mangrove Sediments." Molecules 15, no. 12: 9298-9307.