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Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives
Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, Hubei, China
* Author to whom correspondence should be addressed.
Received: 27 October 2010; in revised form: 18 November 2010 / Accepted: 22 November 2010 / Published: 9 December 2010
Abstract: Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.
Keywords: phenyltriazolinones; strobilurin; herbicidal activity; protoporphyrinogen oxidase
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MDPI and ACS Style
Wu, Q.; Wang, G.; Huang, S.; Lin, L.; Yang, G. Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives. Molecules 2010, 15, 9024-9034.
Wu Q, Wang G, Huang S, Lin L, Yang G. Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives. Molecules. 2010; 15(12):9024-9034.
Wu, Qiongyou; Wang, Guodong; Huang, Shaowei; Lin, Long; Yang, Guangfu. 2010. "Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives." Molecules 15, no. 12: 9024-9034.