Molecules 2010, 15(12), 9024-9034; doi:10.3390/molecules15129024
Article

Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives

Qiongyou Wu* email, Guodong Wang, Shaowei Huang, Long Lin and Guangfu Yang
Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, Hubei, China
* Author to whom correspondence should be addressed.
Received: 27 October 2010; in revised form: 18 November 2010 / Accepted: 22 November 2010 / Published: 9 December 2010
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Abstract: Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.
Keywords: phenyltriazolinones; strobilurin; herbicidal activity; protoporphyrinogen oxidase

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Cite This Article

MDPI and ACS Style

Wu, Q.; Wang, G.; Huang, S.; Lin, L.; Yang, G. Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives. Molecules 2010, 15, 9024-9034.

AMA Style

Wu Q, Wang G, Huang S, Lin L, Yang G. Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives. Molecules. 2010; 15(12):9024-9034.

Chicago/Turabian Style

Wu, Qiongyou; Wang, Guodong; Huang, Shaowei; Lin, Long; Yang, Guangfu. 2010. "Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives." Molecules 15, no. 12: 9024-9034.

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