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Molecules 2010, 15(12), 9024-9034; doi:10.3390/molecules15129024

Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives

Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, Hubei, China
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Received: 27 October 2010 / Revised: 18 November 2010 / Accepted: 22 November 2010 / Published: 9 December 2010
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Abstract

Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.
Keywords: phenyltriazolinones; strobilurin; herbicidal activity; protoporphyrinogen oxidase phenyltriazolinones; strobilurin; herbicidal activity; protoporphyrinogen oxidase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Wu, Q.; Wang, G.; Huang, S.; Lin, L.; Yang, G. Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives. Molecules 2010, 15, 9024-9034.

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