Molecules 2010, 15(12), 8582-8592; doi:10.3390/molecules15128582
Communication

Synthesis of New C2- Symmetric Fluoren-9-ylidene Malonate Derived Bis(oxazoline) Ligands and Their Application in Friedel-Crafts Reactions

email, email, email and * email
Received: 10 November 2010; in revised form: 18 November 2010 / Accepted: 23 November 2010 / Published: 26 November 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A series of new C2-symmetric fluoren-9-ylidene malonate-derived bis(oxazoline) ligands were synthesized from fluoren-9-ylidene malonate and enantiomerically pure amino alcohols via a convenient route. Their asymmetric catalytic properties in the Friedel-Crafts reactions of indoles with arylidene malonates were evaluated, and the Cu(OTf)2 complex of a fluoren-9-ylidene malonate-derived bis(oxazoline) bearing a phenyl group showed moderate to good enantioselectivity (up to 88% ee).
Keywords: bis(oxazoline); fluoren-9-ylidene; asymmetric catalysis; Friedel-Crafts
PDF Full-text Download PDF Full-Text [177 KB, Updated Version, uploaded 18 June 2014 19:35 CEST]
The original version is still available [180 KB, uploaded 18 June 2014 19:35 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Li, J.; Chen, H.-L.; Liu, L.; Fu, B. Synthesis of New C2- Symmetric Fluoren-9-ylidene Malonate Derived Bis(oxazoline) Ligands and Their Application in Friedel-Crafts Reactions. Molecules 2010, 15, 8582-8592.

AMA Style

Li J, Chen H-L, Liu L, Fu B. Synthesis of New C2- Symmetric Fluoren-9-ylidene Malonate Derived Bis(oxazoline) Ligands and Their Application in Friedel-Crafts Reactions. Molecules. 2010; 15(12):8582-8592.

Chicago/Turabian Style

Li, Jing; Chen, Hong-Liang; Liu, Lei; Fu, Bin. 2010. "Synthesis of New C2- Symmetric Fluoren-9-ylidene Malonate Derived Bis(oxazoline) Ligands and Their Application in Friedel-Crafts Reactions." Molecules 15, no. 12: 8582-8592.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert