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Molecules 2010, 15(10), 7106-7114; doi:10.3390/molecules15107106
Article

A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds

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Received: 21 August 2010; in revised form: 23 September 2010 / Accepted: 3 October 2010 / Published: 14 October 2010
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Abstract: Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone (1), together with four known compounds 2-5. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploid embryonic lung cell line MRC-5.
Keywords: Rheedia acuminata; Clusiaceae; xanthones; antiplasmodial activity; cytotoxicity Rheedia acuminata; Clusiaceae; xanthones; antiplasmodial activity; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Marti, G.; Eparvier, V.; Litaudon, M.; Grellier, P.; Guéritte, F. A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds. Molecules 2010, 15, 7106-7114.

AMA Style

Marti G, Eparvier V, Litaudon M, Grellier P, Guéritte F. A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds. Molecules. 2010; 15(10):7106-7114.

Chicago/Turabian Style

Marti, Guillaume; Eparvier, Véronique; Litaudon, Marc; Grellier, Philippe; Guéritte, Françoise. 2010. "A New Xanthone from the Bark Extract of Rheedia acuminata and Antiplasmodial Activity of Its Major Compounds." Molecules 15, no. 10: 7106-7114.


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