Next Article in Journal
Prodigiosin Production by Serratia marcescens UCP 1549 Using Renewable-Resources as a Low Cost Substrate
Next Article in Special Issue
Evaluation of Antioxidant Capacity and Synergistic Associations of Quinonemethide Triterpenes and Phenolic Substances from Maytenus ilicifolia (Celastraceae)
Previous Article in Journal / Special Issue
In Vitro Antioxidant Properties, HIV-1 Reverse Transcriptase and Acetylcholinesterase Inhibitory Effects of Traditional Herbal Preparations Sold in South Africa
Molecules 2010, 15(10), 6905-6930; doi:10.3390/molecules15106905
Review

Natural Antioxidants: Fascinating or Mythical Biomolecules?

,
 and
*
Research Centre for Plant Growth and Development, School of Biological and Conservation Sciences, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa
* Author to whom correspondence should be addressed.
Received: 26 August 2010 / Revised: 9 September 2010 / Accepted: 14 September 2010 / Published: 8 October 2010
(This article belongs to the Special Issue Antioxidants)
Download PDF [327 KB, uploaded 18 June 2014]

Abstract

Research on the use, properties, characteristics and sources of antioxidants especially phenolic compounds, flavonoids, vitamins, synthetic chemicals and some micronutrients began in the late 18th century. Since then antioxidant research has received considerable attention and over a hundred thousand papers have been published on the subject. This has led to a rampant use of antioxidants in order to try to obtain and preserve optimal health. A number of nutraceuticals and food supplements are frequently fortified with synthetic or natural antioxidants. However, some research outcomes have led to the belief that antioxidants exist as mythical biomolecules. This review provides a critical evaluation of some common in vitro antioxidant capacity methods, and a discussion on the role and controversies surrounding non-enzymatic biomolecules, in particular phenolic compounds and non-phenolic compounds, in oxidative processes in an attempt of stemming the tidal wave that is threatening to swamp the concept of natural antioxidants.
Keywords: antioxidants; bioavailability; bio-kinetics; free radicals; phenolic compounds; flavonoids; vitamins antioxidants; bioavailability; bio-kinetics; free radicals; phenolic compounds; flavonoids; vitamins
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Ndhlala, A.R.; Moyo, M.; Van Staden, J. Natural Antioxidants: Fascinating or Mythical Biomolecules? Molecules 2010, 15, 6905-6930.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert